Role of multidetector ct in quantitative enhancement- washout analysis of solid renal masses

Abstract Background Enhancement washout technique in solid renal masses using multidetector computed tomography (MDCT) can differentiate different type of lesions. 99 Patients who are presenting with suspected renal masses or renal tumour for staging are included in this study. CT examination are ca...

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Autores principales:	Shaimaa Alsayed Abdelmegeed, Hesham Mohamed Farok, Medhat Mohamed Refaat, Tarek Abd Elmeneim Eldiasty
Formato:	article
Lenguaje:	EN
Publicado:	SpringerOpen 2021
Materias:	MDCT CCRCC PRCC CHRCC AML CMP Medical physics. Medical radiology. Nuclear medicine R895-920
Acceso en línea:	https://doaj.org/article/0211f684358044de96b5cb2913196eb0
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spelling	oai:doaj.org-article:0211f684358044de96b5cb2913196eb02021-11-21T12:26:51ZRole of multidetector ct in quantitative enhancement- washout analysis of solid renal masses10.1186/s43055-021-00650-72090-4762https://doaj.org/article/0211f684358044de96b5cb2913196eb02021-11-01T00:00:00Zhttps://doi.org/10.1186/s43055-021-00650-7https://doaj.org/toc/2090-4762Abstract Background Enhancement washout technique in solid renal masses using multidetector computed tomography (MDCT) can differentiate different type of lesions. 99 Patients who are presenting with suspected renal masses or renal tumour for staging are included in this study. CT examination are carried out at urology and nephrology centre using MDCT. The attenuation values (Hounsfield Unit) will be assesed for each lesion on the pre enhanced, corticomedullary, nephrographic and delayed phases. Washout ratio will be calculated for each phase of enhancement in comparison to the unenhanced attenuation value. The characteristics of enhancement-washout will be correlated with the final histopathological diagnosis. Results Early enhancement and washout pattern was noted in 54 renal lesions (54.5%) representing 4 types of renal lesions; Oncocytoma (n = 13), clear cell renal cell carcinoma (n = 16), Chromophobe renal cell carcinoma (n = 15) and unclassified renal cell carcinoma (n = 10).Prolonged enhancement pattern was noted 45 lesions (45.4%); PRCC (n = 14), 10 case of lipid poor AML (n = 10), metanephric adenoma (n = 10) and Xp11 RCC (n = 11). High pre-contrast attenuation was noted in Xp 11RCC showing attenuation value 41.7 ± 6.823HU. The highest CMP values were noted in CCRCC (151.9 ± 20.4) followed by oncocytomas (137.6 ± 19.15HU) and then CHRCC (123.6 ± 16.6 HU)while the lowest values were noted in Metanephric adenoma)57.1 ± 17.4HU)and followed by PRCC (59.9 ± 4.8)and followed by lipid poor AML (79.17 ± 13.666) and RCC unclassified (89.06 ± 18.1). Conclusions Four-phase MDCT (the unenhanced, corticomedullary, nephrographic, and excretory phases) evaluate role of MDCT in differentiation of solid renal masses.Shaimaa Alsayed AbdelmegeedHesham Mohamed FarokMedhat Mohamed RefaatTarek Abd Elmeneim EldiastySpringerOpenarticleMDCTCCRCCPRCCCHRCCAMLCMPMedical physics. Medical radiology. Nuclear medicineR895-920ENThe Egyptian Journal of Radiology and Nuclear Medicine, Vol 52, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	MDCT CCRCC PRCC CHRCC AML CMP Medical physics. Medical radiology. Nuclear medicine R895-920
spellingShingle	MDCT CCRCC PRCC CHRCC AML CMP Medical physics. Medical radiology. Nuclear medicine R895-920 Shaimaa Alsayed Abdelmegeed Hesham Mohamed Farok Medhat Mohamed Refaat Tarek Abd Elmeneim Eldiasty Role of multidetector ct in quantitative enhancement- washout analysis of solid renal masses
description	Abstract Background Enhancement washout technique in solid renal masses using multidetector computed tomography (MDCT) can differentiate different type of lesions. 99 Patients who are presenting with suspected renal masses or renal tumour for staging are included in this study. CT examination are carried out at urology and nephrology centre using MDCT. The attenuation values (Hounsfield Unit) will be assesed for each lesion on the pre enhanced, corticomedullary, nephrographic and delayed phases. Washout ratio will be calculated for each phase of enhancement in comparison to the unenhanced attenuation value. The characteristics of enhancement-washout will be correlated with the final histopathological diagnosis. Results Early enhancement and washout pattern was noted in 54 renal lesions (54.5%) representing 4 types of renal lesions; Oncocytoma (n = 13), clear cell renal cell carcinoma (n = 16), Chromophobe renal cell carcinoma (n = 15) and unclassified renal cell carcinoma (n = 10).Prolonged enhancement pattern was noted 45 lesions (45.4%); PRCC (n = 14), 10 case of lipid poor AML (n = 10), metanephric adenoma (n = 10) and Xp11 RCC (n = 11). High pre-contrast attenuation was noted in Xp 11RCC showing attenuation value 41.7 ± 6.823HU. The highest CMP values were noted in CCRCC (151.9 ± 20.4) followed by oncocytomas (137.6 ± 19.15HU) and then CHRCC (123.6 ± 16.6 HU)while the lowest values were noted in Metanephric adenoma)57.1 ± 17.4HU)and followed by PRCC (59.9 ± 4.8)and followed by lipid poor AML (79.17 ± 13.666) and RCC unclassified (89.06 ± 18.1). Conclusions Four-phase MDCT (the unenhanced, corticomedullary, nephrographic, and excretory phases) evaluate role of MDCT in differentiation of solid renal masses.
format	article
author	Shaimaa Alsayed Abdelmegeed Hesham Mohamed Farok Medhat Mohamed Refaat Tarek Abd Elmeneim Eldiasty
author_facet	Shaimaa Alsayed Abdelmegeed Hesham Mohamed Farok Medhat Mohamed Refaat Tarek Abd Elmeneim Eldiasty
author_sort	Shaimaa Alsayed Abdelmegeed
title	Role of multidetector ct in quantitative enhancement- washout analysis of solid renal masses
title_short	Role of multidetector ct in quantitative enhancement- washout analysis of solid renal masses
title_full	Role of multidetector ct in quantitative enhancement- washout analysis of solid renal masses
title_fullStr	Role of multidetector ct in quantitative enhancement- washout analysis of solid renal masses
title_full_unstemmed	Role of multidetector ct in quantitative enhancement- washout analysis of solid renal masses
title_sort	role of multidetector ct in quantitative enhancement- washout analysis of solid renal masses
publisher	SpringerOpen
publishDate	2021
url	https://doaj.org/article/0211f684358044de96b5cb2913196eb0
work_keys_str_mv	AT shaimaaalsayedabdelmegeed roleofmultidetectorctinquantitativeenhancementwashoutanalysisofsolidrenalmasses AT heshammohamedfarok roleofmultidetectorctinquantitativeenhancementwashoutanalysisofsolidrenalmasses AT medhatmohamedrefaat roleofmultidetectorctinquantitativeenhancementwashoutanalysisofsolidrenalmasses AT tarekabdelmeneimeldiasty roleofmultidetectorctinquantitativeenhancementwashoutanalysisofsolidrenalmasses
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Role of multidetector ct in quantitative enhancement- washout analysis of solid renal masses

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