An intermolecular FRET sensor detects the dynamics of T cell receptor clustering

Cellular signalling is often facilitated by membrane protein clustering, but detection of protein clustering at high spatiotemporal resolution is challenging. Here the authors develop a single-chain FRET sensor they name CliF to look at intermolecular associations and dynamics of TCR-CD3 clusters on...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yuanqing Ma, Elvis Pandzic, Philip R. Nicovich, Yui Yamamoto, Joanna Kwiatek, Sophie V. Pageon, Aleš Benda, Jérémie Rossy, Katharina Gaus
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0214fa95f1064f5c88b533788fa353df
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0214fa95f1064f5c88b533788fa353df
record_format	dspace
spelling	oai:doaj.org-article:0214fa95f1064f5c88b533788fa353df2021-12-02T14:42:19ZAn intermolecular FRET sensor detects the dynamics of T cell receptor clustering10.1038/ncomms151002041-1723https://doaj.org/article/0214fa95f1064f5c88b533788fa353df2017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms15100https://doaj.org/toc/2041-1723Cellular signalling is often facilitated by membrane protein clustering, but detection of protein clustering at high spatiotemporal resolution is challenging. Here the authors develop a single-chain FRET sensor they name CliF to look at intermolecular associations and dynamics of TCR-CD3 clusters on the T cell surface.Yuanqing MaElvis PandzicPhilip R. NicovichYui YamamotoJoanna KwiatekSophie V. PageonAleš BendaJérémie RossyKatharina GausNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuanqing Ma Elvis Pandzic Philip R. Nicovich Yui Yamamoto Joanna Kwiatek Sophie V. Pageon Aleš Benda Jérémie Rossy Katharina Gaus An intermolecular FRET sensor detects the dynamics of T cell receptor clustering
description	Cellular signalling is often facilitated by membrane protein clustering, but detection of protein clustering at high spatiotemporal resolution is challenging. Here the authors develop a single-chain FRET sensor they name CliF to look at intermolecular associations and dynamics of TCR-CD3 clusters on the T cell surface.
format	article
author	Yuanqing Ma Elvis Pandzic Philip R. Nicovich Yui Yamamoto Joanna Kwiatek Sophie V. Pageon Aleš Benda Jérémie Rossy Katharina Gaus
author_facet	Yuanqing Ma Elvis Pandzic Philip R. Nicovich Yui Yamamoto Joanna Kwiatek Sophie V. Pageon Aleš Benda Jérémie Rossy Katharina Gaus
author_sort	Yuanqing Ma
title	An intermolecular FRET sensor detects the dynamics of T cell receptor clustering
title_short	An intermolecular FRET sensor detects the dynamics of T cell receptor clustering
title_full	An intermolecular FRET sensor detects the dynamics of T cell receptor clustering
title_fullStr	An intermolecular FRET sensor detects the dynamics of T cell receptor clustering
title_full_unstemmed	An intermolecular FRET sensor detects the dynamics of T cell receptor clustering
title_sort	intermolecular fret sensor detects the dynamics of t cell receptor clustering
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/0214fa95f1064f5c88b533788fa353df
work_keys_str_mv	AT yuanqingma anintermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT elvispandzic anintermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT philiprnicovich anintermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT yuiyamamoto anintermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT joannakwiatek anintermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT sophievpageon anintermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT alesbenda anintermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT jeremierossy anintermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT katharinagaus anintermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT yuanqingma intermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT elvispandzic intermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT philiprnicovich intermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT yuiyamamoto intermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT joannakwiatek intermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT sophievpageon intermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT alesbenda intermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT jeremierossy intermolecularfretsensordetectsthedynamicsoftcellreceptorclustering AT katharinagaus intermolecularfretsensordetectsthedynamicsoftcellreceptorclustering
_version_	1718389729786855424

An intermolecular FRET sensor detects the dynamics of T cell receptor clustering

Ejemplares similares