Pediatric high-grade astrocytoma with piloid features of the spinal cord: A report of two cases and literature review

Although the 2021 World Health Organization classification update of the central nervous system tumors redefined "pilomyxoid astrocytoma" as high-grade astrocytoma with piloid features (HGAP), the craniocerebral HGAP exhibits poorer clinical outcomes when compared to pilocytic astrocytoma....

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Autores principales:	Beibei Yu, Yang Lu, Linkai Jing, Guihuai Wang
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	case report high-grade astrocytomas with piloid features intramedullary pilocytic astrocytoma spinal cord tumor Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/021917fd524c4fdb82977ae12c6651c2
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spelling	oai:doaj.org-article:021917fd524c4fdb82977ae12c6651c22021-11-19T10:42:03ZPediatric high-grade astrocytoma with piloid features of the spinal cord: A report of two cases and literature review2589-61132589-612110.4103/glioma.glioma_10_21https://doaj.org/article/021917fd524c4fdb82977ae12c6651c22021-01-01T00:00:00Zhttp://www.jglioma.com/article.asp?issn=2589-6113;year=2021;volume=4;issue=3;spage=49;epage=53;aulast=Yuhttps://doaj.org/toc/2589-6113https://doaj.org/toc/2589-6121Although the 2021 World Health Organization classification update of the central nervous system tumors redefined "pilomyxoid astrocytoma" as high-grade astrocytoma with piloid features (HGAP), the craniocerebral HGAP exhibits poorer clinical outcomes when compared to pilocytic astrocytoma. However, in the spinal cord, the paucity of information of HGAP cases inhibits the judgment of prognosis and optimal management approaches for patients with spinal HGAP. Here, we summarized the clinical characteristics, management methods, and prognosis of ten cases of spinal HGAP reported in the literature and two cases of spinal HGAP who underwent tumor surgery in our institution. Here, the detailed clinical information we provided may help clinical decision-making for such rare childhood lesions. This study was approved by the Human Research Ethics Committees in our institution on June 29, 2021.Beibei YuYang LuLinkai JingGuihuai WangWolters Kluwer Medknow Publicationsarticlecase reporthigh-grade astrocytomas with piloid featuresintramedullarypilocytic astrocytomaspinal cord tumorNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENGlioma, Vol 4, Iss 3, Pp 49-53 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	case report high-grade astrocytomas with piloid features intramedullary pilocytic astrocytoma spinal cord tumor Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	case report high-grade astrocytomas with piloid features intramedullary pilocytic astrocytoma spinal cord tumor Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Beibei Yu Yang Lu Linkai Jing Guihuai Wang Pediatric high-grade astrocytoma with piloid features of the spinal cord: A report of two cases and literature review
description	Although the 2021 World Health Organization classification update of the central nervous system tumors redefined "pilomyxoid astrocytoma" as high-grade astrocytoma with piloid features (HGAP), the craniocerebral HGAP exhibits poorer clinical outcomes when compared to pilocytic astrocytoma. However, in the spinal cord, the paucity of information of HGAP cases inhibits the judgment of prognosis and optimal management approaches for patients with spinal HGAP. Here, we summarized the clinical characteristics, management methods, and prognosis of ten cases of spinal HGAP reported in the literature and two cases of spinal HGAP who underwent tumor surgery in our institution. Here, the detailed clinical information we provided may help clinical decision-making for such rare childhood lesions. This study was approved by the Human Research Ethics Committees in our institution on June 29, 2021.
format	article
author	Beibei Yu Yang Lu Linkai Jing Guihuai Wang
author_facet	Beibei Yu Yang Lu Linkai Jing Guihuai Wang
author_sort	Beibei Yu
title	Pediatric high-grade astrocytoma with piloid features of the spinal cord: A report of two cases and literature review
title_short	Pediatric high-grade astrocytoma with piloid features of the spinal cord: A report of two cases and literature review
title_full	Pediatric high-grade astrocytoma with piloid features of the spinal cord: A report of two cases and literature review
title_fullStr	Pediatric high-grade astrocytoma with piloid features of the spinal cord: A report of two cases and literature review
title_full_unstemmed	Pediatric high-grade astrocytoma with piloid features of the spinal cord: A report of two cases and literature review
title_sort	pediatric high-grade astrocytoma with piloid features of the spinal cord: a report of two cases and literature review
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/021917fd524c4fdb82977ae12c6651c2
work_keys_str_mv	AT beibeiyu pediatrichighgradeastrocytomawithpiloidfeaturesofthespinalcordareportoftwocasesandliteraturereview AT yanglu pediatrichighgradeastrocytomawithpiloidfeaturesofthespinalcordareportoftwocasesandliteraturereview AT linkaijing pediatrichighgradeastrocytomawithpiloidfeaturesofthespinalcordareportoftwocasesandliteraturereview AT guihuaiwang pediatrichighgradeastrocytomawithpiloidfeaturesofthespinalcordareportoftwocasesandliteraturereview
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Pediatric high-grade astrocytoma with piloid features of the spinal cord: A report of two cases and literature review

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