The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis

Stem cell competition mediates the balance between tissue homeostasis and tumour formation, but how this occurs is unclear. Here, Singh et al.show that the tumour suppressor Mlfl-adaptor molecule regulates the balance between germline stem cell and somatic cyst stem cell growth in the Drosophila tes...

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Autores principales: Shree Ram Singh, Ying Liu, Jiangsha Zhao, Xiankun Zeng, Steven X. Hou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/021bf51ffdc54e10a26d8a0c0a27697b
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Sumario:Stem cell competition mediates the balance between tissue homeostasis and tumour formation, but how this occurs is unclear. Here, Singh et al.show that the tumour suppressor Mlfl-adaptor molecule regulates the balance between germline stem cell and somatic cyst stem cell growth in the Drosophila testis niche.