The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis
Stem cell competition mediates the balance between tissue homeostasis and tumour formation, but how this occurs is unclear. Here, Singh et al.show that the tumour suppressor Mlfl-adaptor molecule regulates the balance between germline stem cell and somatic cyst stem cell growth in the Drosophila tes...
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2016
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oai:doaj.org-article:021bf51ffdc54e10a26d8a0c0a27697b2021-12-02T17:33:21ZThe novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis10.1038/ncomms104732041-1723https://doaj.org/article/021bf51ffdc54e10a26d8a0c0a27697b2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10473https://doaj.org/toc/2041-1723Stem cell competition mediates the balance between tissue homeostasis and tumour formation, but how this occurs is unclear. Here, Singh et al.show that the tumour suppressor Mlfl-adaptor molecule regulates the balance between germline stem cell and somatic cyst stem cell growth in the Drosophila testis niche.Shree Ram SinghYing LiuJiangsha ZhaoXiankun ZengSteven X. HouNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016) |
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Science Q Shree Ram Singh Ying Liu Jiangsha Zhao Xiankun Zeng Steven X. Hou The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis |
| description |
Stem cell competition mediates the balance between tissue homeostasis and tumour formation, but how this occurs is unclear. Here, Singh et al.show that the tumour suppressor Mlfl-adaptor molecule regulates the balance between germline stem cell and somatic cyst stem cell growth in the Drosophila testis niche. |
| format |
article |
| author |
Shree Ram Singh Ying Liu Jiangsha Zhao Xiankun Zeng Steven X. Hou |
| author_facet |
Shree Ram Singh Ying Liu Jiangsha Zhao Xiankun Zeng Steven X. Hou |
| author_sort |
Shree Ram Singh |
| title |
The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis |
| title_short |
The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis |
| title_full |
The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis |
| title_fullStr |
The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis |
| title_full_unstemmed |
The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis |
| title_sort |
novel tumour suppressor madm regulates stem cell competition in the drosophila testis |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/021bf51ffdc54e10a26d8a0c0a27697b |
| work_keys_str_mv |
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| _version_ |
1718379920073162752 |