The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis

The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis

Stem cell competition mediates the balance between tissue homeostasis and tumour formation, but how this occurs is unclear. Here, Singh et al.show that the tumour suppressor Mlfl-adaptor molecule regulates the balance between germline stem cell and somatic cyst stem cell growth in the Drosophila tes...

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Autores principales: Shree Ram Singh, Ying Liu, Jiangsha Zhao, Xiankun Zeng, Steven X. Hou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/021bf51ffdc54e10a26d8a0c0a27697b
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spelling oai:doaj.org-article:021bf51ffdc54e10a26d8a0c0a27697b2021-12-02T17:33:21ZThe novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis10.1038/ncomms104732041-1723https://doaj.org/article/021bf51ffdc54e10a26d8a0c0a27697b2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10473https://doaj.org/toc/2041-1723Stem cell competition mediates the balance between tissue homeostasis and tumour formation, but how this occurs is unclear. Here, Singh et al.show that the tumour suppressor Mlfl-adaptor molecule regulates the balance between germline stem cell and somatic cyst stem cell growth in the Drosophila testis niche.Shree Ram SinghYing LiuJiangsha ZhaoXiankun ZengSteven X. HouNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shree Ram Singh
Ying Liu
Jiangsha Zhao
Xiankun Zeng
Steven X. Hou
The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis
description Stem cell competition mediates the balance between tissue homeostasis and tumour formation, but how this occurs is unclear. Here, Singh et al.show that the tumour suppressor Mlfl-adaptor molecule regulates the balance between germline stem cell and somatic cyst stem cell growth in the Drosophila testis niche.
format article
author Shree Ram Singh
Ying Liu
Jiangsha Zhao
Xiankun Zeng
Steven X. Hou
author_facet Shree Ram Singh
Ying Liu
Jiangsha Zhao
Xiankun Zeng
Steven X. Hou
author_sort Shree Ram Singh
title The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis
title_short The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis
title_full The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis
title_fullStr The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis
title_full_unstemmed The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis
title_sort novel tumour suppressor madm regulates stem cell competition in the drosophila testis
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/021bf51ffdc54e10a26d8a0c0a27697b
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