Effect of Vitamin-D Supplementation on Recurrence of Acute Otitis Media in Pre-School Children

Background: Acute Otitis media (AOM) and its recurrence is a prevalent health problem among pre-school children. Different strategies to prevent recurrent have been established with questionable efficacy. Vitamin D is suspected as a possible preventable risk factor. Aim of the work:To evaluate the...

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Autores principales:	Osama Refaat, El Bakry Tharwat, Ahmed El-Gamal
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2020
Materias:	vitamin-d recurrent otitis media upper respiratory infection pre-school children Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/021c86bf27154429ba358920f0860c16
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spelling	oai:doaj.org-article:021c86bf27154429ba358920f0860c162021-12-02T13:52:45ZEffect of Vitamin-D Supplementation on Recurrence of Acute Otitis Media in Pre-School Children2636-41742682-378010.21608/ijma.2020.34138.1141https://doaj.org/article/021c86bf27154429ba358920f0860c162020-07-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_104865_fbf06f6461756442ffacf3461d64e5aa.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Acute Otitis media (AOM) and its recurrence is a prevalent health problem among pre-school children. Different strategies to prevent recurrent have been established with questionable efficacy. Vitamin D is suspected as a possible preventable risk factor. Aim of the work:To evaluate the effect of vitamin-D supplementation on recurrence rate of acute otitis media among Pre-school children. Patients and Methods:60 pre-school children with a recurrent episode of acute otitis media [by history and otoscopic examination] were included. After diagnosis, all children received standard treatment and after recovery, serum levels of vitamin-D were estimated; those with reduced vitamin D had been included, then divided into: Study group (30 children, received oral vitamin-D supplementation for 4 months; and Control group (30 children; received placebo). New attacks of AOM had been document during the regular visits for the six months. Vitamin D had been re-estimated after 6 months. Results: Both groups were comparable regarding studied variables at the start. Upper respiratory tract infection and ear discharge significantly decreased; vitamin D significantly increased among study group at 6 months. Recurrent AOM after 6 months, had been significantly reduced among study vs control group (1.43±0.62 vs 3.46±0.62 respectively). Also, vitamin-D significantly increased at the end in study vs control group (21.76±5.95 vs 14.53±4.73 ng/ml respectively). The mean percentage of increase of vitamin-D in study group was 135.98% compared to 33.91%. In control group. Conclusion: Vitamin D supplementation to children with a history of rAOM plays a significant role in reduction of attack frequency.Osama RefaatEl Bakry TharwatAhmed El-GamalAl-Azhar University, Faculty of Medicine (Damietta)articlevitamin-drecurrent otitis mediaupper respiratory infectionpre-schoolchildrenMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 2, Iss 3, Pp 604-610 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	vitamin-d recurrent otitis media upper respiratory infection pre-school children Medicine (General) R5-920
spellingShingle	vitamin-d recurrent otitis media upper respiratory infection pre-school children Medicine (General) R5-920 Osama Refaat El Bakry Tharwat Ahmed El-Gamal Effect of Vitamin-D Supplementation on Recurrence of Acute Otitis Media in Pre-School Children
description	Background: Acute Otitis media (AOM) and its recurrence is a prevalent health problem among pre-school children. Different strategies to prevent recurrent have been established with questionable efficacy. Vitamin D is suspected as a possible preventable risk factor. Aim of the work:To evaluate the effect of vitamin-D supplementation on recurrence rate of acute otitis media among Pre-school children. Patients and Methods:60 pre-school children with a recurrent episode of acute otitis media [by history and otoscopic examination] were included. After diagnosis, all children received standard treatment and after recovery, serum levels of vitamin-D were estimated; those with reduced vitamin D had been included, then divided into: Study group (30 children, received oral vitamin-D supplementation for 4 months; and Control group (30 children; received placebo). New attacks of AOM had been document during the regular visits for the six months. Vitamin D had been re-estimated after 6 months. Results: Both groups were comparable regarding studied variables at the start. Upper respiratory tract infection and ear discharge significantly decreased; vitamin D significantly increased among study group at 6 months. Recurrent AOM after 6 months, had been significantly reduced among study vs control group (1.43±0.62 vs 3.46±0.62 respectively). Also, vitamin-D significantly increased at the end in study vs control group (21.76±5.95 vs 14.53±4.73 ng/ml respectively). The mean percentage of increase of vitamin-D in study group was 135.98% compared to 33.91%. In control group. Conclusion: Vitamin D supplementation to children with a history of rAOM plays a significant role in reduction of attack frequency.
format	article
author	Osama Refaat El Bakry Tharwat Ahmed El-Gamal
author_facet	Osama Refaat El Bakry Tharwat Ahmed El-Gamal
author_sort	Osama Refaat
title	Effect of Vitamin-D Supplementation on Recurrence of Acute Otitis Media in Pre-School Children
title_short	Effect of Vitamin-D Supplementation on Recurrence of Acute Otitis Media in Pre-School Children
title_full	Effect of Vitamin-D Supplementation on Recurrence of Acute Otitis Media in Pre-School Children
title_fullStr	Effect of Vitamin-D Supplementation on Recurrence of Acute Otitis Media in Pre-School Children
title_full_unstemmed	Effect of Vitamin-D Supplementation on Recurrence of Acute Otitis Media in Pre-School Children
title_sort	effect of vitamin-d supplementation on recurrence of acute otitis media in pre-school children
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2020
url	https://doaj.org/article/021c86bf27154429ba358920f0860c16
work_keys_str_mv	AT osamarefaat effectofvitamindsupplementationonrecurrenceofacuteotitismediainpreschoolchildren AT elbakrytharwat effectofvitamindsupplementationonrecurrenceofacuteotitismediainpreschoolchildren AT ahmedelgamal effectofvitamindsupplementationonrecurrenceofacuteotitismediainpreschoolchildren
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Effect of Vitamin-D Supplementation on Recurrence of Acute Otitis Media in Pre-School Children

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