Ferroptosis: New Dawn for Overcoming the Cardio-Cerebrovascular Diseases
The dynamic balance of cardiomyocytes and neurons is essential to maintain the normal physiological functions of heart and brain. If excessive cells die in tissues, serious Cardio-Cerebrovascular Diseases would occur, namely, hypertension, myocardial infarction, and ischemic stroke. The regulation o...
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Frontiers Media S.A.
2021
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oai:doaj.org-article:021d8332bb0e4163acc34edbd323dd2b2021-11-11T10:02:25ZFerroptosis: New Dawn for Overcoming the Cardio-Cerebrovascular Diseases2296-634X10.3389/fcell.2021.733908https://doaj.org/article/021d8332bb0e4163acc34edbd323dd2b2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fcell.2021.733908/fullhttps://doaj.org/toc/2296-634XThe dynamic balance of cardiomyocytes and neurons is essential to maintain the normal physiological functions of heart and brain. If excessive cells die in tissues, serious Cardio-Cerebrovascular Diseases would occur, namely, hypertension, myocardial infarction, and ischemic stroke. The regulation of cell death plays a role in promoting or alleviating Cardio-Cerebrovascular Diseases. Ferroptosis is an iron-dependent new type of cell death that has been proved to occur in a variety of diseases. In our review, we focus on the critical role of ferroptosis and its regulatory mechanisms involved in Cardio-Cerebrovascular Diseases, and discuss the important function of ferroptosis-related inhibitors in order to propose potential implications for the prevention and treatment of Cardio-Cerebrovascular Diseases.Meng-Yi LuoMeng-Yi LuoJian-Hui SuJian-Hui SuShao-Xin GongNa LiangWen-Qian HuangWen-Qian HuangWei ChenWei ChenAi-Ping WangAi-Ping WangYing TianFrontiers Media S.A.articleferroptosiscardio-cerebrovascular diseaseinflammationironlipid peroxidationBiology (General)QH301-705.5ENFrontiers in Cell and Developmental Biology, Vol 9 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
ferroptosis cardio-cerebrovascular disease inflammation iron lipid peroxidation Biology (General) QH301-705.5 |
| spellingShingle |
ferroptosis cardio-cerebrovascular disease inflammation iron lipid peroxidation Biology (General) QH301-705.5 Meng-Yi Luo Meng-Yi Luo Jian-Hui Su Jian-Hui Su Shao-Xin Gong Na Liang Wen-Qian Huang Wen-Qian Huang Wei Chen Wei Chen Ai-Ping Wang Ai-Ping Wang Ying Tian Ferroptosis: New Dawn for Overcoming the Cardio-Cerebrovascular Diseases |
| description |
The dynamic balance of cardiomyocytes and neurons is essential to maintain the normal physiological functions of heart and brain. If excessive cells die in tissues, serious Cardio-Cerebrovascular Diseases would occur, namely, hypertension, myocardial infarction, and ischemic stroke. The regulation of cell death plays a role in promoting or alleviating Cardio-Cerebrovascular Diseases. Ferroptosis is an iron-dependent new type of cell death that has been proved to occur in a variety of diseases. In our review, we focus on the critical role of ferroptosis and its regulatory mechanisms involved in Cardio-Cerebrovascular Diseases, and discuss the important function of ferroptosis-related inhibitors in order to propose potential implications for the prevention and treatment of Cardio-Cerebrovascular Diseases. |
| format |
article |
| author |
Meng-Yi Luo Meng-Yi Luo Jian-Hui Su Jian-Hui Su Shao-Xin Gong Na Liang Wen-Qian Huang Wen-Qian Huang Wei Chen Wei Chen Ai-Ping Wang Ai-Ping Wang Ying Tian |
| author_facet |
Meng-Yi Luo Meng-Yi Luo Jian-Hui Su Jian-Hui Su Shao-Xin Gong Na Liang Wen-Qian Huang Wen-Qian Huang Wei Chen Wei Chen Ai-Ping Wang Ai-Ping Wang Ying Tian |
| author_sort |
Meng-Yi Luo |
| title |
Ferroptosis: New Dawn for Overcoming the Cardio-Cerebrovascular Diseases |
| title_short |
Ferroptosis: New Dawn for Overcoming the Cardio-Cerebrovascular Diseases |
| title_full |
Ferroptosis: New Dawn for Overcoming the Cardio-Cerebrovascular Diseases |
| title_fullStr |
Ferroptosis: New Dawn for Overcoming the Cardio-Cerebrovascular Diseases |
| title_full_unstemmed |
Ferroptosis: New Dawn for Overcoming the Cardio-Cerebrovascular Diseases |
| title_sort |
ferroptosis: new dawn for overcoming the cardio-cerebrovascular diseases |
| publisher |
Frontiers Media S.A. |
| publishDate |
2021 |
| url |
https://doaj.org/article/021d8332bb0e4163acc34edbd323dd2b |
| work_keys_str_mv |
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