Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization

Hyperpolarized metabolic contrast agents for magnetic resonance imaging can provide non-invasive and realtime information on tissue specific aberrant metabolism, but producing and handling them is highly demanding because of their short lifetime. Here a solid sample extraction, storage, and transpor...

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Autores principales:	Andrea Capozzi, Jan Kilund, Magnus Karlsson, Saket Patel, Arthur Cesar Pinon, François Vibert, Olivier Ouari, Mathilde H. Lerche, Jan Henrik Ardenkjær-Larsen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/02205f4eb13a4a5196a0a6fb9e88e441
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spelling	oai:doaj.org-article:02205f4eb13a4a5196a0a6fb9e88e4412021-12-02T18:02:40ZMetabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization10.1038/s42004-021-00536-92399-3669https://doaj.org/article/02205f4eb13a4a5196a0a6fb9e88e4412021-06-01T00:00:00Zhttps://doi.org/10.1038/s42004-021-00536-9https://doaj.org/toc/2399-3669Hyperpolarized metabolic contrast agents for magnetic resonance imaging can provide non-invasive and realtime information on tissue specific aberrant metabolism, but producing and handling them is highly demanding because of their short lifetime. Here a solid sample extraction, storage, and transport technique allows disconnecting production from end-user sites handling, as well as hour-long lifetimes of the agents.Andrea CapozziJan KilundMagnus KarlssonSaket PatelArthur Cesar PinonFrançois VibertOlivier OuariMathilde H. LercheJan Henrik Ardenkjær-LarsenNature PortfolioarticleChemistryQD1-999ENCommunications Chemistry, Vol 4, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Chemistry QD1-999
spellingShingle	Chemistry QD1-999 Andrea Capozzi Jan Kilund Magnus Karlsson Saket Patel Arthur Cesar Pinon François Vibert Olivier Ouari Mathilde H. Lerche Jan Henrik Ardenkjær-Larsen Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization
description	Hyperpolarized metabolic contrast agents for magnetic resonance imaging can provide non-invasive and realtime information on tissue specific aberrant metabolism, but producing and handling them is highly demanding because of their short lifetime. Here a solid sample extraction, storage, and transport technique allows disconnecting production from end-user sites handling, as well as hour-long lifetimes of the agents.
format	article
author	Andrea Capozzi Jan Kilund Magnus Karlsson Saket Patel Arthur Cesar Pinon François Vibert Olivier Ouari Mathilde H. Lerche Jan Henrik Ardenkjær-Larsen
author_facet	Andrea Capozzi Jan Kilund Magnus Karlsson Saket Patel Arthur Cesar Pinon François Vibert Olivier Ouari Mathilde H. Lerche Jan Henrik Ardenkjær-Larsen
author_sort	Andrea Capozzi
title	Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization
title_short	Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization
title_full	Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization
title_fullStr	Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization
title_full_unstemmed	Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization
title_sort	metabolic contrast agents produced from transported solid 13c-glucose hyperpolarized via dynamic nuclear polarization
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/02205f4eb13a4a5196a0a6fb9e88e441
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Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization

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