The role of inflammation in the pathogenesis of perinatal depression and offspring outcomes
The role of inflammation in the pathogenesis of depression is becoming increasingly apparent, but its role in perinatal depression is less well-studied. Pregnancy and the postpartum are characterised by distinct and changing inflammatory profiles throughout, which makes the study of depression-relat...
Guardado en:
Autor principal: | |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/0223eeaae86e4060afdfda9fb811e925 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:0223eeaae86e4060afdfda9fb811e925 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:0223eeaae86e4060afdfda9fb811e9252021-11-28T04:38:40ZThe role of inflammation in the pathogenesis of perinatal depression and offspring outcomes2666-354610.1016/j.bbih.2021.100390https://doaj.org/article/0223eeaae86e4060afdfda9fb811e9252021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2666354621001939https://doaj.org/toc/2666-3546The role of inflammation in the pathogenesis of depression is becoming increasingly apparent, but its role in perinatal depression is less well-studied. Pregnancy and the postpartum are characterised by distinct and changing inflammatory profiles throughout, which makes the study of depression-related alterations in this period complex. This review presents literature discussing a role for the immune system in both antenatal and postnatal depression. Furthermore, literature investigating the role of the maternal immune system on breast milk composition and offspring immunological and behavioural outcomes is discussed, before concluding with suggestions for future work as this developing field grows.Kristi M. SawyerElsevierarticlePerinatalAntenatalPostnatalDepressionInflammationBreast milkNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENBrain, Behavior, & Immunity - Health, Vol 18, Iss , Pp 100390- (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Perinatal Antenatal Postnatal Depression Inflammation Breast milk Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 |
spellingShingle |
Perinatal Antenatal Postnatal Depression Inflammation Breast milk Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Kristi M. Sawyer The role of inflammation in the pathogenesis of perinatal depression and offspring outcomes |
description |
The role of inflammation in the pathogenesis of depression is becoming increasingly apparent, but its role in perinatal depression is less well-studied. Pregnancy and the postpartum are characterised by distinct and changing inflammatory profiles throughout, which makes the study of depression-related alterations in this period complex. This review presents literature discussing a role for the immune system in both antenatal and postnatal depression. Furthermore, literature investigating the role of the maternal immune system on breast milk composition and offspring immunological and behavioural outcomes is discussed, before concluding with suggestions for future work as this developing field grows. |
format |
article |
author |
Kristi M. Sawyer |
author_facet |
Kristi M. Sawyer |
author_sort |
Kristi M. Sawyer |
title |
The role of inflammation in the pathogenesis of perinatal depression and offspring outcomes |
title_short |
The role of inflammation in the pathogenesis of perinatal depression and offspring outcomes |
title_full |
The role of inflammation in the pathogenesis of perinatal depression and offspring outcomes |
title_fullStr |
The role of inflammation in the pathogenesis of perinatal depression and offspring outcomes |
title_full_unstemmed |
The role of inflammation in the pathogenesis of perinatal depression and offspring outcomes |
title_sort |
role of inflammation in the pathogenesis of perinatal depression and offspring outcomes |
publisher |
Elsevier |
publishDate |
2021 |
url |
https://doaj.org/article/0223eeaae86e4060afdfda9fb811e925 |
work_keys_str_mv |
AT kristimsawyer theroleofinflammationinthepathogenesisofperinataldepressionandoffspringoutcomes AT kristimsawyer roleofinflammationinthepathogenesisofperinataldepressionandoffspringoutcomes |
_version_ |
1718408237376602112 |