G3BP1 controls the senescence-associated secretome and its impact on cancer progression
The mechanisms that control the deleterious behaviour of senescent cells is unclear. Here, the authors show that G3BP1 is required for the induction of the senescence-associated secretory phenotype (SASP), without affecting senescence, and that SASP secretion is a primary mediator of senescence-asso...
Guardado en:
Autores principales: | Amr Omer, Monica Cruz Barrera, Julian L. Moran, Xian J. Lian, Sergio Di Marco, Christian Beausejour, Imed-Eddine Gallouzi |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/02292b1787c3465190c76cee31b72257 |
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