Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy
Exercise induces expression of the myokine Irisin. Here the authors show that Irisin promotes muscle hypertrophy and regeneration following injury or denervation in mice, by activating satellite cells and modulating protein synthesis and degradation.
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Nature Portfolio
2017
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Acceso en línea: | https://doaj.org/article/022ea72749724adc87af9bed20ab0411 |
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oai:doaj.org-article:022ea72749724adc87af9bed20ab04112021-12-02T14:40:56ZIrisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy10.1038/s41467-017-01131-02041-1723https://doaj.org/article/022ea72749724adc87af9bed20ab04112017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01131-0https://doaj.org/toc/2041-1723Exercise induces expression of the myokine Irisin. Here the authors show that Irisin promotes muscle hypertrophy and regeneration following injury or denervation in mice, by activating satellite cells and modulating protein synthesis and degradation.Musarrat Maisha RezaNathiya SubramaniyamChu Ming SimXiaojia GeDurgalakshmi SathiakumarCraig McFarlaneMridula SharmaRavi KambadurNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-17 (2017) |
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Science Q Musarrat Maisha Reza Nathiya Subramaniyam Chu Ming Sim Xiaojia Ge Durgalakshmi Sathiakumar Craig McFarlane Mridula Sharma Ravi Kambadur Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy |
description |
Exercise induces expression of the myokine Irisin. Here the authors show that Irisin promotes muscle hypertrophy and regeneration following injury or denervation in mice, by activating satellite cells and modulating protein synthesis and degradation. |
format |
article |
author |
Musarrat Maisha Reza Nathiya Subramaniyam Chu Ming Sim Xiaojia Ge Durgalakshmi Sathiakumar Craig McFarlane Mridula Sharma Ravi Kambadur |
author_facet |
Musarrat Maisha Reza Nathiya Subramaniyam Chu Ming Sim Xiaojia Ge Durgalakshmi Sathiakumar Craig McFarlane Mridula Sharma Ravi Kambadur |
author_sort |
Musarrat Maisha Reza |
title |
Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy |
title_short |
Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy |
title_full |
Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy |
title_fullStr |
Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy |
title_full_unstemmed |
Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy |
title_sort |
irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/022ea72749724adc87af9bed20ab0411 |
work_keys_str_mv |
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1718390032890331136 |