Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy

Exercise induces expression of the myokine Irisin. Here the authors show that Irisin promotes muscle hypertrophy and regeneration following injury or denervation in mice, by activating satellite cells and modulating protein synthesis and degradation.

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Autores principales: Musarrat Maisha Reza, Nathiya Subramaniyam, Chu Ming Sim, Xiaojia Ge, Durgalakshmi Sathiakumar, Craig McFarlane, Mridula Sharma, Ravi Kambadur
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/022ea72749724adc87af9bed20ab0411
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spelling oai:doaj.org-article:022ea72749724adc87af9bed20ab04112021-12-02T14:40:56ZIrisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy10.1038/s41467-017-01131-02041-1723https://doaj.org/article/022ea72749724adc87af9bed20ab04112017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01131-0https://doaj.org/toc/2041-1723Exercise induces expression of the myokine Irisin. Here the authors show that Irisin promotes muscle hypertrophy and regeneration following injury or denervation in mice, by activating satellite cells and modulating protein synthesis and degradation.Musarrat Maisha RezaNathiya SubramaniyamChu Ming SimXiaojia GeDurgalakshmi SathiakumarCraig McFarlaneMridula SharmaRavi KambadurNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Musarrat Maisha Reza
Nathiya Subramaniyam
Chu Ming Sim
Xiaojia Ge
Durgalakshmi Sathiakumar
Craig McFarlane
Mridula Sharma
Ravi Kambadur
Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy
description Exercise induces expression of the myokine Irisin. Here the authors show that Irisin promotes muscle hypertrophy and regeneration following injury or denervation in mice, by activating satellite cells and modulating protein synthesis and degradation.
format article
author Musarrat Maisha Reza
Nathiya Subramaniyam
Chu Ming Sim
Xiaojia Ge
Durgalakshmi Sathiakumar
Craig McFarlane
Mridula Sharma
Ravi Kambadur
author_facet Musarrat Maisha Reza
Nathiya Subramaniyam
Chu Ming Sim
Xiaojia Ge
Durgalakshmi Sathiakumar
Craig McFarlane
Mridula Sharma
Ravi Kambadur
author_sort Musarrat Maisha Reza
title Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy
title_short Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy
title_full Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy
title_fullStr Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy
title_full_unstemmed Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy
title_sort irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/022ea72749724adc87af9bed20ab0411
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AT xiaojiage irisinisapromyogenicfactorthatinducesskeletalmusclehypertrophyandrescuesdenervationinducedatrophy
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