Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy
Exercise induces expression of the myokine Irisin. Here the authors show that Irisin promotes muscle hypertrophy and regeneration following injury or denervation in mice, by activating satellite cells and modulating protein synthesis and degradation.
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Autores principales: | Musarrat Maisha Reza, Nathiya Subramaniyam, Chu Ming Sim, Xiaojia Ge, Durgalakshmi Sathiakumar, Craig McFarlane, Mridula Sharma, Ravi Kambadur |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/022ea72749724adc87af9bed20ab0411 |
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