Identification of modified peptides using localization-aware open search
Mass spectrometry-based proteomics is the method of choice for the global mapping of post-translational modifications, but matching and scoring peaks with unknown masses remains challenging. Here, the authors present a refined open search strategy to score all peaks with higher sensitivity and accur...
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Autores principales: | Fengchao Yu, Guo Ci Teo, Andy T. Kong, Sarah E. Haynes, Dmitry M. Avtonomov, Daniel J. Geiszler, Alexey I. Nesvizhskii |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/02387a43c32348a9b61aa02e3a3e2a42 |
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