MNase titration reveals differences between nucleosome occupancy and chromatin accessibility

Nucleosome positioning and chromatin accessibility are important contributors to the regulation of gene expression. Here the authors describe a method that allows the simultaneous measurement of nucleosome occupancy and chromatin accessibility in the same assay, revealing new features of chromatin o...

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Autores principales:	Jakub Mieczkowski, April Cook, Sarah K. Bowman, Britta Mueller, Burak H. Alver, Sharmistha Kundu, Aimee M. Deaton, Jennifer A. Urban, Erica Larschan, Peter J. Park, Robert E. Kingston, Michael Y. Tolstorukov
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0238a8cab20c4061987b9392b7b9bc4e
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spelling	oai:doaj.org-article:0238a8cab20c4061987b9392b7b9bc4e2021-12-02T16:50:55ZMNase titration reveals differences between nucleosome occupancy and chromatin accessibility10.1038/ncomms114852041-1723https://doaj.org/article/0238a8cab20c4061987b9392b7b9bc4e2016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11485https://doaj.org/toc/2041-1723Nucleosome positioning and chromatin accessibility are important contributors to the regulation of gene expression. Here the authors describe a method that allows the simultaneous measurement of nucleosome occupancy and chromatin accessibility in the same assay, revealing new features of chromatin organization linked to gene regulation.Jakub MieczkowskiApril CookSarah K. BowmanBritta MuellerBurak H. AlverSharmistha KunduAimee M. DeatonJennifer A. UrbanErica LarschanPeter J. ParkRobert E. KingstonMichael Y. TolstorukovNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jakub Mieczkowski April Cook Sarah K. Bowman Britta Mueller Burak H. Alver Sharmistha Kundu Aimee M. Deaton Jennifer A. Urban Erica Larschan Peter J. Park Robert E. Kingston Michael Y. Tolstorukov MNase titration reveals differences between nucleosome occupancy and chromatin accessibility
description	Nucleosome positioning and chromatin accessibility are important contributors to the regulation of gene expression. Here the authors describe a method that allows the simultaneous measurement of nucleosome occupancy and chromatin accessibility in the same assay, revealing new features of chromatin organization linked to gene regulation.
format	article
author	Jakub Mieczkowski April Cook Sarah K. Bowman Britta Mueller Burak H. Alver Sharmistha Kundu Aimee M. Deaton Jennifer A. Urban Erica Larschan Peter J. Park Robert E. Kingston Michael Y. Tolstorukov
author_facet	Jakub Mieczkowski April Cook Sarah K. Bowman Britta Mueller Burak H. Alver Sharmistha Kundu Aimee M. Deaton Jennifer A. Urban Erica Larschan Peter J. Park Robert E. Kingston Michael Y. Tolstorukov
author_sort	Jakub Mieczkowski
title	MNase titration reveals differences between nucleosome occupancy and chromatin accessibility
title_short	MNase titration reveals differences between nucleosome occupancy and chromatin accessibility
title_full	MNase titration reveals differences between nucleosome occupancy and chromatin accessibility
title_fullStr	MNase titration reveals differences between nucleosome occupancy and chromatin accessibility
title_full_unstemmed	MNase titration reveals differences between nucleosome occupancy and chromatin accessibility
title_sort	mnase titration reveals differences between nucleosome occupancy and chromatin accessibility
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/0238a8cab20c4061987b9392b7b9bc4e
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MNase titration reveals differences between nucleosome occupancy and chromatin accessibility

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