Anemia among adult HIV patients in Ethiopia: a hospital-based cross-sectional study

Hermela Melese,1 Molla Mesele Wassie,2 Haile Woldie,2 Abilo Tadesse,3 Nebiyu Mesfin3 1HIV Follow-up Care Clinic, Debre-Tabor Hospital, Debre‑Tabor, 2Department of Human Nutrition, Institute of Public Health, 3Department of Internal Medicine, School of Medicine, College of Medicine and Health Science...

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Autores principales:	Melese H, Wassie MM, Woldie H, Tadesse A, Mesfin N
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Key words: Anemia HIV/AIDS Antiretroviral treatment AZT-toxicity Ethiopia. Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/023dd9e955ea45088fdc4d3a02530bf7
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spelling	oai:doaj.org-article:023dd9e955ea45088fdc4d3a02530bf72021-12-02T08:45:06ZAnemia among adult HIV patients in Ethiopia: a hospital-based cross-sectional study1179-1373https://doaj.org/article/023dd9e955ea45088fdc4d3a02530bf72017-02-01T00:00:00Zhttps://www.dovepress.com/anemia-among-adult-hiv-patients-in-ethiopia-a-hospital-based-cross-sec-peer-reviewed-article-HIVhttps://doaj.org/toc/1179-1373Hermela Melese,1 Molla Mesele Wassie,2 Haile Woldie,2 Abilo Tadesse,3 Nebiyu Mesfin3 1HIV Follow-up Care Clinic, Debre-Tabor Hospital, Debre‑Tabor, 2Department of Human Nutrition, Institute of Public Health, 3Department of Internal Medicine, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia Background: Anemia is a major public health problem in HIV patients around the world. It has a negative effect on the quality of life of HIV patients and progression of the HIV disease. In the sub-Saharan African setting, including Ethiopia where both HIV infection and under-nutrition are expected to be high, there is a paucity of data on the matter. This study was aimed to reveal the magnitude and factors associated with anemia among adult HIV patients in Debre-Tabor Hospital, northwest Ethiopia. Methods: A hospital-based cross-sectional study was used among adult HIV patients in Debre-Tabor Hospital from April 1 to May 30, 2015. The diagnosis of anemia was made following the 2011 World Health Organization recommendation on hemoglobin cut-off points. Univariable and multivariable logistic regression was carried out to assess factors associated with anemia. Results: A total of 377 patients’ charts were reviewed. Most of the participants (n=237, 62.9%) were taking antiretroviral treatment (ART). The overall prevalence of anemia was 23% (95% CI: 19.1, 27.6). Being ART-naïve (adjusted odds ratio [AOR]: 3.37; 95% CI: 1.59, 7.14), having treatment history with anti-tuberculosis (TB) drug (AOR: 3.2; 95% CI: 1.19, 8.67), taking zidovudine (ZDV)-containing ART regimen (AOR: 2.14; 95% CI: 1.03, 4.57), and having recent CD4+ T-lymphocytes count of <200 cells/µL (AOR: 2.13; 95% CI: 1.04, 4.36) were associated with occurrence of anemia among adult HIV patients. Conclusion and recommendation: Anemia continues to be a major co-morbidity among adult HIV patients in Ethiopia. Adult HIV patients who are taking ZDV-containing ART, with a history of TB treatment, have a low CD4+T-lymphocytes count and are ART-naïve should be carefully screened and treated for anemia. Keywords: anemia, HIV/AIDS, antiretroviral treatment, ZDV toxicity, EthiopiaMelese HWassie MMWoldie HTadesse AMesfin NDove Medical PressarticleKey words: AnemiaHIV/AIDSAntiretroviral treatmentAZT-toxicityEthiopia.Immunologic diseases. AllergyRC581-607ENHIV/AIDS: Research and Palliative Care, Vol Volume 9, Pp 25-30 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Key words: Anemia HIV/AIDS Antiretroviral treatment AZT-toxicity Ethiopia. Immunologic diseases. Allergy RC581-607
spellingShingle	Key words: Anemia HIV/AIDS Antiretroviral treatment AZT-toxicity Ethiopia. Immunologic diseases. Allergy RC581-607 Melese H Wassie MM Woldie H Tadesse A Mesfin N Anemia among adult HIV patients in Ethiopia: a hospital-based cross-sectional study
description	Hermela Melese,1 Molla Mesele Wassie,2 Haile Woldie,2 Abilo Tadesse,3 Nebiyu Mesfin3 1HIV Follow-up Care Clinic, Debre-Tabor Hospital, Debre‑Tabor, 2Department of Human Nutrition, Institute of Public Health, 3Department of Internal Medicine, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia Background: Anemia is a major public health problem in HIV patients around the world. It has a negative effect on the quality of life of HIV patients and progression of the HIV disease. In the sub-Saharan African setting, including Ethiopia where both HIV infection and under-nutrition are expected to be high, there is a paucity of data on the matter. This study was aimed to reveal the magnitude and factors associated with anemia among adult HIV patients in Debre-Tabor Hospital, northwest Ethiopia. Methods: A hospital-based cross-sectional study was used among adult HIV patients in Debre-Tabor Hospital from April 1 to May 30, 2015. The diagnosis of anemia was made following the 2011 World Health Organization recommendation on hemoglobin cut-off points. Univariable and multivariable logistic regression was carried out to assess factors associated with anemia. Results: A total of 377 patients’ charts were reviewed. Most of the participants (n=237, 62.9%) were taking antiretroviral treatment (ART). The overall prevalence of anemia was 23% (95% CI: 19.1, 27.6). Being ART-naïve (adjusted odds ratio [AOR]: 3.37; 95% CI: 1.59, 7.14), having treatment history with anti-tuberculosis (TB) drug (AOR: 3.2; 95% CI: 1.19, 8.67), taking zidovudine (ZDV)-containing ART regimen (AOR: 2.14; 95% CI: 1.03, 4.57), and having recent CD4+ T-lymphocytes count of <200 cells/µL (AOR: 2.13; 95% CI: 1.04, 4.36) were associated with occurrence of anemia among adult HIV patients. Conclusion and recommendation: Anemia continues to be a major co-morbidity among adult HIV patients in Ethiopia. Adult HIV patients who are taking ZDV-containing ART, with a history of TB treatment, have a low CD4+T-lymphocytes count and are ART-naïve should be carefully screened and treated for anemia. Keywords: anemia, HIV/AIDS, antiretroviral treatment, ZDV toxicity, Ethiopia
format	article
author	Melese H Wassie MM Woldie H Tadesse A Mesfin N
author_facet	Melese H Wassie MM Woldie H Tadesse A Mesfin N
author_sort	Melese H
title	Anemia among adult HIV patients in Ethiopia: a hospital-based cross-sectional study
title_short	Anemia among adult HIV patients in Ethiopia: a hospital-based cross-sectional study
title_full	Anemia among adult HIV patients in Ethiopia: a hospital-based cross-sectional study
title_fullStr	Anemia among adult HIV patients in Ethiopia: a hospital-based cross-sectional study
title_full_unstemmed	Anemia among adult HIV patients in Ethiopia: a hospital-based cross-sectional study
title_sort	anemia among adult hiv patients in ethiopia: a hospital-based cross-sectional study
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/023dd9e955ea45088fdc4d3a02530bf7
work_keys_str_mv	AT meleseh anemiaamongadulthivpatientsinethiopiaahospitalbasedcrosssectionalstudy AT wassiemm anemiaamongadulthivpatientsinethiopiaahospitalbasedcrosssectionalstudy AT woldieh anemiaamongadulthivpatientsinethiopiaahospitalbasedcrosssectionalstudy AT tadessea anemiaamongadulthivpatientsinethiopiaahospitalbasedcrosssectionalstudy AT mesfinn anemiaamongadulthivpatientsinethiopiaahospitalbasedcrosssectionalstudy
_version_	1718398342904414208

Anemia among adult HIV patients in Ethiopia: a hospital-based cross-sectional study

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