Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre

Following instruction by a morphogen secreting centre, aggregates of mouse embryonic stem cells develop into embryo-like structures organized around an axial mesoderm, which show extensive characteristics of a neurula-stage mouse embryo, with antero-posterior and dorso-ventral patterning of germ lay...

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Autores principales:	Peng-Fei Xu, Ricardo Moraes Borges, Jonathan Fillatre, Maraysa de Oliveira-Melo, Tao Cheng, Bernard Thisse, Christine Thisse
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0246bf48802949329082b7c4d63be793
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spelling	oai:doaj.org-article:0246bf48802949329082b7c4d63be7932021-12-02T15:02:29ZConstruction of a mammalian embryo model from stem cells organized by a morphogen signalling centre10.1038/s41467-021-23653-42041-1723https://doaj.org/article/0246bf48802949329082b7c4d63be7932021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23653-4https://doaj.org/toc/2041-1723Following instruction by a morphogen secreting centre, aggregates of mouse embryonic stem cells develop into embryo-like structures organized around an axial mesoderm, which show extensive characteristics of a neurula-stage mouse embryo, with antero-posterior and dorso-ventral patterning of germ layer derivatives.Peng-Fei XuRicardo Moraes BorgesJonathan FillatreMaraysa de Oliveira-MeloTao ChengBernard ThisseChristine ThisseNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Peng-Fei Xu Ricardo Moraes Borges Jonathan Fillatre Maraysa de Oliveira-Melo Tao Cheng Bernard Thisse Christine Thisse Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre
description	Following instruction by a morphogen secreting centre, aggregates of mouse embryonic stem cells develop into embryo-like structures organized around an axial mesoderm, which show extensive characteristics of a neurula-stage mouse embryo, with antero-posterior and dorso-ventral patterning of germ layer derivatives.
format	article
author	Peng-Fei Xu Ricardo Moraes Borges Jonathan Fillatre Maraysa de Oliveira-Melo Tao Cheng Bernard Thisse Christine Thisse
author_facet	Peng-Fei Xu Ricardo Moraes Borges Jonathan Fillatre Maraysa de Oliveira-Melo Tao Cheng Bernard Thisse Christine Thisse
author_sort	Peng-Fei Xu
title	Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre
title_short	Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre
title_full	Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre
title_fullStr	Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre
title_full_unstemmed	Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre
title_sort	construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0246bf48802949329082b7c4d63be793
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Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre

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