Apraxia for differentiating Alzheimer’s disease from subcortical vascular dementia and mild cognitive impairment

Apraxia for differentiating Alzheimer’s disease from subcortical vascular dementia and mild cognitive impairment

Serhat Ozkan,1 Demet Ozbabalik Adapinar,1 Nese Tuncer Elmaci,2 Didem Arslantas31Department of Neurology, Eskisehir Osmangazi University Medical Faculty, Eskisehir, Turkey; 2Department of Neurology, Marmara University Medical Faculty, Istanbul, Turkey; 3Department of Public Health, Eskisehir Osmangaz...

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Autores principales: Ozkan S, Adapinar DO, Elmaci NT, Arslantas D
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2013
Materias:
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Acceso en línea:https://doaj.org/article/024722a0fcae40bda106b6cdde6bcb27
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spelling oai:doaj.org-article:024722a0fcae40bda106b6cdde6bcb272021-12-02T07:19:18ZApraxia for differentiating Alzheimer’s disease from subcortical vascular dementia and mild cognitive impairment1176-63281178-2021https://doaj.org/article/024722a0fcae40bda106b6cdde6bcb272013-07-01T00:00:00Zhttp://www.dovepress.com/apraxia-for-differentiating-alzheimerrsquos-disease-from-subcortical-v-a13619https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Serhat Ozkan,1 Demet Ozbabalik Adapinar,1 Nese Tuncer Elmaci,2 Didem Arslantas31Department of Neurology, Eskisehir Osmangazi University Medical Faculty, Eskisehir, Turkey; 2Department of Neurology, Marmara University Medical Faculty, Istanbul, Turkey; 3Department of Public Health, Eskisehir Osmangazi University Medical Faculty, Eskisehir, TurkeyAbstract: Although ideomotor limb apraxia is considered to be a typical sign of cortical pathologies such as Alzheimer’s disease (AD), it has been also reported in subcortical neurodegenerative diseases and vascular lesions. We aimed to investigate the difference between AD, subcortical vascular dementia (SVaD) and mild cognitive impairment (MCI) patients by means of ideomotor limb apraxia frequency and severity. Ninety-six AD, 72 SVaD, and 84 MCI patients were assessed with the mini-mental status examination (MMSE), clinical dementia rating (CDR) and the apraxia screening test of TULIA (AST). Apraxia was significantly more frequent in the AD patients (32.3%) than in both of the SVaD (16.7%) and MCI (4.8%) patients. The frequency of apraxia was also significantly higher in SVaD patients than in MCI patients. AD patients had significantly lower apraxia scores than both SVaD and MCI patients. In addition, a significant difference was found between SVaD and MCI patients in terms of apraxia scores. These results suggest that the widespread belief of the association between apraxia and cortical dementias is not exactly correct. The significant difference between both of the dementia groups and the MCI patients suggests that the absence of apraxia can be an indicator for MCI diagnosis.Keywords: apraxia, Alzheimer’s disease, subcortical vascular dementia, mild cognitive impairmentOzkan SAdapinar DOElmaci NTArslantas DDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2013, Iss default, Pp 947-951 (2013)
institution DOAJ
collection DOAJ
language EN
topic Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Ozkan S
Adapinar DO
Elmaci NT
Arslantas D
Apraxia for differentiating Alzheimer’s disease from subcortical vascular dementia and mild cognitive impairment
description Serhat Ozkan,1 Demet Ozbabalik Adapinar,1 Nese Tuncer Elmaci,2 Didem Arslantas31Department of Neurology, Eskisehir Osmangazi University Medical Faculty, Eskisehir, Turkey; 2Department of Neurology, Marmara University Medical Faculty, Istanbul, Turkey; 3Department of Public Health, Eskisehir Osmangazi University Medical Faculty, Eskisehir, TurkeyAbstract: Although ideomotor limb apraxia is considered to be a typical sign of cortical pathologies such as Alzheimer’s disease (AD), it has been also reported in subcortical neurodegenerative diseases and vascular lesions. We aimed to investigate the difference between AD, subcortical vascular dementia (SVaD) and mild cognitive impairment (MCI) patients by means of ideomotor limb apraxia frequency and severity. Ninety-six AD, 72 SVaD, and 84 MCI patients were assessed with the mini-mental status examination (MMSE), clinical dementia rating (CDR) and the apraxia screening test of TULIA (AST). Apraxia was significantly more frequent in the AD patients (32.3%) than in both of the SVaD (16.7%) and MCI (4.8%) patients. The frequency of apraxia was also significantly higher in SVaD patients than in MCI patients. AD patients had significantly lower apraxia scores than both SVaD and MCI patients. In addition, a significant difference was found between SVaD and MCI patients in terms of apraxia scores. These results suggest that the widespread belief of the association between apraxia and cortical dementias is not exactly correct. The significant difference between both of the dementia groups and the MCI patients suggests that the absence of apraxia can be an indicator for MCI diagnosis.Keywords: apraxia, Alzheimer’s disease, subcortical vascular dementia, mild cognitive impairment
format article
author Ozkan S
Adapinar DO
Elmaci NT
Arslantas D
author_facet Ozkan S
Adapinar DO
Elmaci NT
Arslantas D
author_sort Ozkan S
title Apraxia for differentiating Alzheimer’s disease from subcortical vascular dementia and mild cognitive impairment
title_short Apraxia for differentiating Alzheimer’s disease from subcortical vascular dementia and mild cognitive impairment
title_full Apraxia for differentiating Alzheimer’s disease from subcortical vascular dementia and mild cognitive impairment
title_fullStr Apraxia for differentiating Alzheimer’s disease from subcortical vascular dementia and mild cognitive impairment
title_full_unstemmed Apraxia for differentiating Alzheimer’s disease from subcortical vascular dementia and mild cognitive impairment
title_sort apraxia for differentiating alzheimer’s disease from subcortical vascular dementia and mild cognitive impairment
publisher Dove Medical Press
publishDate 2013
url https://doaj.org/article/024722a0fcae40bda106b6cdde6bcb27
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AT elmacint apraxiafordifferentiatingalzheimerrsquosdiseasefromsubcorticalvasculardementiaandmildcognitiveimpairment
AT arslantasd apraxiafordifferentiatingalzheimerrsquosdiseasefromsubcorticalvasculardementiaandmildcognitiveimpairment
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