Serratia marcescens as a cause of unfavorable outcome in the twin pregnancy

Several Serratia species are widely distributed in nature, but Serratia marcescens is the only species frequently isolated in hospitals. This pathogen is mainly responsible for nosocomial infection, mostly in immunocompromised hosts. A 26-year-old woman with a twin pregnancy, regularly controlled, w...

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Autores principales:	Kljakić Duško, Milosavljević Miloš Z., Jovanović Milan, Popović Vesna Čolaković, Raičević Saša
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2020
Materias:	twins dizygotic fetal growth retardation premature birth infectious pregnancy complications serratia marcescens Medicine R
Acceso en línea:	https://doaj.org/article/024afcc2870747eda4d7a5ecf0a2a4b1
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spelling	oai:doaj.org-article:024afcc2870747eda4d7a5ecf0a2a4b12021-12-05T14:10:53ZSerratia marcescens as a cause of unfavorable outcome in the twin pregnancy2391-546310.1515/med-2021-0205https://doaj.org/article/024afcc2870747eda4d7a5ecf0a2a4b12020-12-01T00:00:00Zhttps://doi.org/10.1515/med-2021-0205https://doaj.org/toc/2391-5463Several Serratia species are widely distributed in nature, but Serratia marcescens is the only species frequently isolated in hospitals. This pathogen is mainly responsible for nosocomial infection, mostly in immunocompromised hosts. A 26-year-old woman with a twin pregnancy, regularly controlled, was hospitalized at 24 + 5 weeks of gestation due to scant vaginal bleeding, lower abdominal pain, and body temperature up to 37.5°C. Gynecological examination revealed bleeding accompanied by dilatation of the cervix. The laboratory analyses revealed leukocytosis with elevated C-reactive protein (CRP). Treatment was initiated with intravenous antibiotic administration. After admission, fetal membranes spontaneously ruptured, and an extremely preterm dichorionic female twin birth occurred at 25 + 0 weeks of gestation. Both infants died two days after labor. Pathological and microbiological analyses revealed chorioamnionitis caused by S. marcescens. According to the antibiogram, antibiotic treatment was continued for the next 7 days. The examination of cervical and vaginal discharge samples was negative three days and two weeks after therapy. S. marcescens may cause spontaneous miscarriages and, in this important case, caused loss of discordant twins in an extremely preterm birth by an immunocompetent patient. Infection by S. marcescens cannot be excluded as a cause of discordant growth and needs to be confirmed by further research.Kljakić DuškoMilosavljević Miloš Z.Jovanović MilanPopović Vesna ČolakovićRaičević SašaDe Gruyterarticletwins dizygoticfetal growth retardationpremature birthinfectious pregnancy complicationsserratia marcescensMedicineRENOpen Medicine, Vol 16, Iss 1, Pp 81-86 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	twins dizygotic fetal growth retardation premature birth infectious pregnancy complications serratia marcescens Medicine R
spellingShingle	twins dizygotic fetal growth retardation premature birth infectious pregnancy complications serratia marcescens Medicine R Kljakić Duško Milosavljević Miloš Z. Jovanović Milan Popović Vesna Čolaković Raičević Saša Serratia marcescens as a cause of unfavorable outcome in the twin pregnancy
description	Several Serratia species are widely distributed in nature, but Serratia marcescens is the only species frequently isolated in hospitals. This pathogen is mainly responsible for nosocomial infection, mostly in immunocompromised hosts. A 26-year-old woman with a twin pregnancy, regularly controlled, was hospitalized at 24 + 5 weeks of gestation due to scant vaginal bleeding, lower abdominal pain, and body temperature up to 37.5°C. Gynecological examination revealed bleeding accompanied by dilatation of the cervix. The laboratory analyses revealed leukocytosis with elevated C-reactive protein (CRP). Treatment was initiated with intravenous antibiotic administration. After admission, fetal membranes spontaneously ruptured, and an extremely preterm dichorionic female twin birth occurred at 25 + 0 weeks of gestation. Both infants died two days after labor. Pathological and microbiological analyses revealed chorioamnionitis caused by S. marcescens. According to the antibiogram, antibiotic treatment was continued for the next 7 days. The examination of cervical and vaginal discharge samples was negative three days and two weeks after therapy. S. marcescens may cause spontaneous miscarriages and, in this important case, caused loss of discordant twins in an extremely preterm birth by an immunocompetent patient. Infection by S. marcescens cannot be excluded as a cause of discordant growth and needs to be confirmed by further research.
format	article
author	Kljakić Duško Milosavljević Miloš Z. Jovanović Milan Popović Vesna Čolaković Raičević Saša
author_facet	Kljakić Duško Milosavljević Miloš Z. Jovanović Milan Popović Vesna Čolaković Raičević Saša
author_sort	Kljakić Duško
title	Serratia marcescens as a cause of unfavorable outcome in the twin pregnancy
title_short	Serratia marcescens as a cause of unfavorable outcome in the twin pregnancy
title_full	Serratia marcescens as a cause of unfavorable outcome in the twin pregnancy
title_fullStr	Serratia marcescens as a cause of unfavorable outcome in the twin pregnancy
title_full_unstemmed	Serratia marcescens as a cause of unfavorable outcome in the twin pregnancy
title_sort	serratia marcescens as a cause of unfavorable outcome in the twin pregnancy
publisher	De Gruyter
publishDate	2020
url	https://doaj.org/article/024afcc2870747eda4d7a5ecf0a2a4b1
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Serratia marcescens as a cause of unfavorable outcome in the twin pregnancy

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