Impact of obesity and type 2 diabetes on health-related quality of life in the general population in England

Stephen CL Gough,1 Nana Kragh,2 Uffe Jon Ploug,2 Mette Hammer21University of Birmingham and University Hospital Birmingham NHS Foundation Trust, Birmingham, UK; 2Novo Nordisk A/S Global Health Economics and Outcomes Research Krogshojvej 55, DK-2880 Bagsvaerd, DenmarkBackground: Weight gain can contr...

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Autores principales:	Stephen CL Gough, Nana Kragh, Uffe Jon Ploug, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2009
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/0256ea820a4f41f994b47040e0dc3118
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spelling	oai:doaj.org-article:0256ea820a4f41f994b47040e0dc31182021-12-02T01:16:23ZImpact of obesity and type 2 diabetes on health-related quality of life in the general population in England1178-7007https://doaj.org/article/0256ea820a4f41f994b47040e0dc31182009-11-01T00:00:00Zhttp://www.dovepress.com/impact-of-obesity-and-type-2-diabetes-on-health-related-quality-of-lif-a3686https://doaj.org/toc/1178-7007Stephen CL Gough,1 Nana Kragh,2 Uffe Jon Ploug,2 Mette Hammer21University of Birmingham and University Hospital Birmingham NHS Foundation Trust, Birmingham, UK; 2Novo Nordisk A/S Global Health Economics and Outcomes Research Krogshojvej 55, DK-2880 Bagsvaerd, DenmarkBackground: Weight gain can contribute towards the development of type 2 diabetes (T2D), and some treatments for T2D can lead to weight gain. The aim of this study was to determine whether having T2D and also being obese had a greater or lesser impact on health-related quality of life (HRQoL) than having either of the two conditions alone.Methods: The 2003 dataset of the Health Survey for England (HSE) was analyzed using multiple regression analyses to examine the influence of obesity and T2D on HRQoL, and to determine whether there was any interaction between these two disutilities.Results: T2D reduced HRQoL by 0.029 points, and obesity reduced HRQoL by 0.027 points. There was no significant interaction effect between T2D and obesity, suggesting that the effect of having both T2D and being obese is simply additive and results in a reduction in HRQoL of 0.056.Conclusions: Based on analysis of HSE 2003 data, people with either T2D or obesity experience significant reduction in HRQoL and people with both conditions have a reduction in HRQoL equal to the sum of the two independent effects. The effect of obesity on HRQoL in people with T2D should be considered when selecting a therapy.Keywords: diabetes, health-related quality of life, obesity, type 2 diabetes, England Stephen CL GoughNana KraghUffe Jon Plouget alDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2009, Iss default, Pp 179-184 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Stephen CL Gough Nana Kragh Uffe Jon Ploug et al Impact of obesity and type 2 diabetes on health-related quality of life in the general population in England
description	Stephen CL Gough,1 Nana Kragh,2 Uffe Jon Ploug,2 Mette Hammer21University of Birmingham and University Hospital Birmingham NHS Foundation Trust, Birmingham, UK; 2Novo Nordisk A/S Global Health Economics and Outcomes Research Krogshojvej 55, DK-2880 Bagsvaerd, DenmarkBackground: Weight gain can contribute towards the development of type 2 diabetes (T2D), and some treatments for T2D can lead to weight gain. The aim of this study was to determine whether having T2D and also being obese had a greater or lesser impact on health-related quality of life (HRQoL) than having either of the two conditions alone.Methods: The 2003 dataset of the Health Survey for England (HSE) was analyzed using multiple regression analyses to examine the influence of obesity and T2D on HRQoL, and to determine whether there was any interaction between these two disutilities.Results: T2D reduced HRQoL by 0.029 points, and obesity reduced HRQoL by 0.027 points. There was no significant interaction effect between T2D and obesity, suggesting that the effect of having both T2D and being obese is simply additive and results in a reduction in HRQoL of 0.056.Conclusions: Based on analysis of HSE 2003 data, people with either T2D or obesity experience significant reduction in HRQoL and people with both conditions have a reduction in HRQoL equal to the sum of the two independent effects. The effect of obesity on HRQoL in people with T2D should be considered when selecting a therapy.Keywords: diabetes, health-related quality of life, obesity, type 2 diabetes, England
format	article
author	Stephen CL Gough Nana Kragh Uffe Jon Ploug et al
author_facet	Stephen CL Gough Nana Kragh Uffe Jon Ploug et al
author_sort	Stephen CL Gough
title	Impact of obesity and type 2 diabetes on health-related quality of life in the general population in England
title_short	Impact of obesity and type 2 diabetes on health-related quality of life in the general population in England
title_full	Impact of obesity and type 2 diabetes on health-related quality of life in the general population in England
title_fullStr	Impact of obesity and type 2 diabetes on health-related quality of life in the general population in England
title_full_unstemmed	Impact of obesity and type 2 diabetes on health-related quality of life in the general population in England
title_sort	impact of obesity and type 2 diabetes on health-related quality of life in the general population in england
publisher	Dove Medical Press
publishDate	2009
url	https://doaj.org/article/0256ea820a4f41f994b47040e0dc3118
work_keys_str_mv	AT stephenclgough impactofobesityandtype2diabetesonhealthrelatedqualityoflifeinthegeneralpopulationinengland AT nanakragh impactofobesityandtype2diabetesonhealthrelatedqualityoflifeinthegeneralpopulationinengland AT uffejonploug impactofobesityandtype2diabetesonhealthrelatedqualityoflifeinthegeneralpopulationinengland AT etal impactofobesityandtype2diabetesonhealthrelatedqualityoflifeinthegeneralpopulationinengland
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Impact of obesity and type 2 diabetes on health-related quality of life in the general population in England

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