m<sup>6</sup>A mRNA Methylation Regulates LKB1 to Promote Autophagy of Hepatoblastoma Cells through Upregulated Phosphorylation of AMPK

m<sup>6</sup>A mRNA Methylation Regulates LKB1 to Promote Autophagy of Hepatoblastoma Cells through Upregulated Phosphorylation of AMPK

The N6-methyladenosine (m<sup>6</sup>A) RNA modification can regulate autophagy to modulate the growth and development of tumors, but the mechanism of m6A modification for the regulation of autophagy in hepatocellular carcinoma cells (HCC) remains unclear. In the study, the knockdown of...

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Autores principales: Guohui Li, Liang Deng, Nan Huang, Zhongqi Cui, Qi Wu, Ji Ma, Qiuhui Pan, Fenyong Sun
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
WTAP
HCC
autophagy
LKB1
AMPK
Genetics
QH426-470
Acceso en línea:https://doaj.org/article/025bb92f8f504f13a146f7016e08e295
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