Synchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report
Adult patients with B-cell acute lymphoblastic leukemia (ALL) have higher rates of antecedent and subsequent malignancies. However, synchronous identification of ALL and ovarian cancer is exceedingly rare. We report the unique case of a 65-year-old woman with synchronous B-cell ALL and low-grade ser...
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Karger Publishers
2021
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oai:doaj.org-article:025c95be9a3e4d4888a3df2be64eeebb2021-12-02T12:40:23ZSynchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report1662-657510.1159/000519743https://doaj.org/article/025c95be9a3e4d4888a3df2be64eeebb2021-11-01T00:00:00Zhttps://www.karger.com/Article/FullText/519743https://doaj.org/toc/1662-6575Adult patients with B-cell acute lymphoblastic leukemia (ALL) have higher rates of antecedent and subsequent malignancies. However, synchronous identification of ALL and ovarian cancer is exceedingly rare. We report the unique case of a 65-year-old woman with synchronous B-cell ALL and low-grade serous ovarian carcinoma diagnosed after surgical intervention for a small bowel obstruction. Treatment with inotuzumab ozogamicin followed by adnexal mass resection and postoperative letrozole was successful in achieving complete remission for both her leukemia and ovarian cancer.Michael SuperdockJustin KomisarofHani KaterjiEric HuseltonKarger Publishersarticleleukemiaovarian carcinomamalignancyNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCase Reports in Oncology, Vol 14, Iss 3, Pp 1621-1626 (2021) |
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leukemia ovarian carcinoma malignancy Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
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leukemia ovarian carcinoma malignancy Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Michael Superdock Justin Komisarof Hani Katerji Eric Huselton Synchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report |
description |
Adult patients with B-cell acute lymphoblastic leukemia (ALL) have higher rates of antecedent and subsequent malignancies. However, synchronous identification of ALL and ovarian cancer is exceedingly rare. We report the unique case of a 65-year-old woman with synchronous B-cell ALL and low-grade serous ovarian carcinoma diagnosed after surgical intervention for a small bowel obstruction. Treatment with inotuzumab ozogamicin followed by adnexal mass resection and postoperative letrozole was successful in achieving complete remission for both her leukemia and ovarian cancer. |
format |
article |
author |
Michael Superdock Justin Komisarof Hani Katerji Eric Huselton |
author_facet |
Michael Superdock Justin Komisarof Hani Katerji Eric Huselton |
author_sort |
Michael Superdock |
title |
Synchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report |
title_short |
Synchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report |
title_full |
Synchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report |
title_fullStr |
Synchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report |
title_full_unstemmed |
Synchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report |
title_sort |
synchronous b-cell acute lymphoblastic leukemia and serous ovarian carcinoma: a case report |
publisher |
Karger Publishers |
publishDate |
2021 |
url |
https://doaj.org/article/025c95be9a3e4d4888a3df2be64eeebb |
work_keys_str_mv |
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_version_ |
1718393721749241856 |