Synchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report

Adult patients with B-cell acute lymphoblastic leukemia (ALL) have higher rates of antecedent and subsequent malignancies. However, synchronous identification of ALL and ovarian cancer is exceedingly rare. We report the unique case of a 65-year-old woman with synchronous B-cell ALL and low-grade ser...

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Autores principales: Michael Superdock, Justin Komisarof, Hani Katerji, Eric Huselton
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Lenguaje:EN
Publicado: Karger Publishers 2021
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Acceso en línea:https://doaj.org/article/025c95be9a3e4d4888a3df2be64eeebb
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spelling oai:doaj.org-article:025c95be9a3e4d4888a3df2be64eeebb2021-12-02T12:40:23ZSynchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report1662-657510.1159/000519743https://doaj.org/article/025c95be9a3e4d4888a3df2be64eeebb2021-11-01T00:00:00Zhttps://www.karger.com/Article/FullText/519743https://doaj.org/toc/1662-6575Adult patients with B-cell acute lymphoblastic leukemia (ALL) have higher rates of antecedent and subsequent malignancies. However, synchronous identification of ALL and ovarian cancer is exceedingly rare. We report the unique case of a 65-year-old woman with synchronous B-cell ALL and low-grade serous ovarian carcinoma diagnosed after surgical intervention for a small bowel obstruction. Treatment with inotuzumab ozogamicin followed by adnexal mass resection and postoperative letrozole was successful in achieving complete remission for both her leukemia and ovarian cancer.Michael SuperdockJustin KomisarofHani KaterjiEric HuseltonKarger Publishersarticleleukemiaovarian carcinomamalignancyNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCase Reports in Oncology, Vol 14, Iss 3, Pp 1621-1626 (2021)
institution DOAJ
collection DOAJ
language EN
topic leukemia
ovarian carcinoma
malignancy
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
spellingShingle leukemia
ovarian carcinoma
malignancy
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Michael Superdock
Justin Komisarof
Hani Katerji
Eric Huselton
Synchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report
description Adult patients with B-cell acute lymphoblastic leukemia (ALL) have higher rates of antecedent and subsequent malignancies. However, synchronous identification of ALL and ovarian cancer is exceedingly rare. We report the unique case of a 65-year-old woman with synchronous B-cell ALL and low-grade serous ovarian carcinoma diagnosed after surgical intervention for a small bowel obstruction. Treatment with inotuzumab ozogamicin followed by adnexal mass resection and postoperative letrozole was successful in achieving complete remission for both her leukemia and ovarian cancer.
format article
author Michael Superdock
Justin Komisarof
Hani Katerji
Eric Huselton
author_facet Michael Superdock
Justin Komisarof
Hani Katerji
Eric Huselton
author_sort Michael Superdock
title Synchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report
title_short Synchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report
title_full Synchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report
title_fullStr Synchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report
title_full_unstemmed Synchronous B-Cell Acute Lymphoblastic Leukemia and Serous Ovarian Carcinoma: A Case Report
title_sort synchronous b-cell acute lymphoblastic leukemia and serous ovarian carcinoma: a case report
publisher Karger Publishers
publishDate 2021
url https://doaj.org/article/025c95be9a3e4d4888a3df2be64eeebb
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AT erichuselton synchronousbcellacutelymphoblasticleukemiaandserousovariancarcinomaacasereport
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