Functional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy

Two-photon microscopy is a powerful tool for studying neuronal activity but cannot easily image deeper cortical layers. Here, the authors design a custom microscope for three-photon microscopy and use it to reveal response properties of layer 5, 6, and subplate visual cortical neurons.

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Autores principales:	Murat Yildirim, Hiroki Sugihara, Peter T. C. So, Mriganka Sur
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/026c5287de584c509e5a5115ae25ff45
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spelling	oai:doaj.org-article:026c5287de584c509e5a5115ae25ff452021-12-02T14:38:37ZFunctional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy10.1038/s41467-018-08179-62041-1723https://doaj.org/article/026c5287de584c509e5a5115ae25ff452019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08179-6https://doaj.org/toc/2041-1723Two-photon microscopy is a powerful tool for studying neuronal activity but cannot easily image deeper cortical layers. Here, the authors design a custom microscope for three-photon microscopy and use it to reveal response properties of layer 5, 6, and subplate visual cortical neurons.Murat YildirimHiroki SugiharaPeter T. C. SoMriganka SurNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Murat Yildirim Hiroki Sugihara Peter T. C. So Mriganka Sur Functional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy
description	Two-photon microscopy is a powerful tool for studying neuronal activity but cannot easily image deeper cortical layers. Here, the authors design a custom microscope for three-photon microscopy and use it to reveal response properties of layer 5, 6, and subplate visual cortical neurons.
format	article
author	Murat Yildirim Hiroki Sugihara Peter T. C. So Mriganka Sur
author_facet	Murat Yildirim Hiroki Sugihara Peter T. C. So Mriganka Sur
author_sort	Murat Yildirim
title	Functional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy
title_short	Functional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy
title_full	Functional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy
title_fullStr	Functional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy
title_full_unstemmed	Functional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy
title_sort	functional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/026c5287de584c509e5a5115ae25ff45
work_keys_str_mv	AT muratyildirim functionalimagingofvisualcorticallayersandsubplateinawakemicewithoptimizedthreephotonmicroscopy AT hirokisugihara functionalimagingofvisualcorticallayersandsubplateinawakemicewithoptimizedthreephotonmicroscopy AT petertcso functionalimagingofvisualcorticallayersandsubplateinawakemicewithoptimizedthreephotonmicroscopy AT mrigankasur functionalimagingofvisualcorticallayersandsubplateinawakemicewithoptimizedthreephotonmicroscopy
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Functional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy

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