Acute loss of the hepatic endo-lysosomal system in vivo causes compensatory changes in iron homeostasis

Acute loss of the hepatic endo-lysosomal system in vivo causes compensatory changes in iron homeostasis

Abstract Liver cells communicate with the extracellular environment to take up nutrients via endocytosis. Iron uptake is essential for metabolic activities and cell homeostasis. Here, we investigated the role of the endocytic system for maintaining iron homeostasis. We specifically depleted the smal...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Christoph Metzendorf, Anja Zeigerer, Sarah Seifert, Richard Sparla, Bahar Najafi, François Canonne-Hergaux, Marino Zerial, Martina U. Muckenthaler
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/02702bebeda441eca74b0906443eaff0
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares