High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes

Nucleosomes compact the genome and regulate access to specific DNA sequences. Here the authors employ single-molecule FRET studies to characterize nucleosome dynamics at different salt concentrations and dissect nucleosome disassembly into elementary steps.

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Autores principales: Alexander Gansen, Suren Felekyan, Ralf Kühnemuth, Kathrin Lehmann, Katalin Tóth, Claus A. M. Seidel, Jörg Langowski
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/027c6235d43c47e7b8c91fcf0e44bef1
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spelling oai:doaj.org-article:027c6235d43c47e7b8c91fcf0e44bef12021-12-02T17:33:04ZHigh precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes10.1038/s41467-018-06758-12041-1723https://doaj.org/article/027c6235d43c47e7b8c91fcf0e44bef12018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06758-1https://doaj.org/toc/2041-1723Nucleosomes compact the genome and regulate access to specific DNA sequences. Here the authors employ single-molecule FRET studies to characterize nucleosome dynamics at different salt concentrations and dissect nucleosome disassembly into elementary steps.Alexander GansenSuren FelekyanRalf KühnemuthKathrin LehmannKatalin TóthClaus A. M. SeidelJörg LangowskiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alexander Gansen
Suren Felekyan
Ralf Kühnemuth
Kathrin Lehmann
Katalin Tóth
Claus A. M. Seidel
Jörg Langowski
High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes
description Nucleosomes compact the genome and regulate access to specific DNA sequences. Here the authors employ single-molecule FRET studies to characterize nucleosome dynamics at different salt concentrations and dissect nucleosome disassembly into elementary steps.
format article
author Alexander Gansen
Suren Felekyan
Ralf Kühnemuth
Kathrin Lehmann
Katalin Tóth
Claus A. M. Seidel
Jörg Langowski
author_facet Alexander Gansen
Suren Felekyan
Ralf Kühnemuth
Kathrin Lehmann
Katalin Tóth
Claus A. M. Seidel
Jörg Langowski
author_sort Alexander Gansen
title High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes
title_short High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes
title_full High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes
title_fullStr High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes
title_full_unstemmed High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes
title_sort high precision fret studies reveal reversible transitions in nucleosomes between microseconds and minutes
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/027c6235d43c47e7b8c91fcf0e44bef1
work_keys_str_mv AT alexandergansen highprecisionfretstudiesrevealreversibletransitionsinnucleosomesbetweenmicrosecondsandminutes
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AT kathrinlehmann highprecisionfretstudiesrevealreversibletransitionsinnucleosomesbetweenmicrosecondsandminutes
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