High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes
Nucleosomes compact the genome and regulate access to specific DNA sequences. Here the authors employ single-molecule FRET studies to characterize nucleosome dynamics at different salt concentrations and dissect nucleosome disassembly into elementary steps.
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Nature Portfolio
2018
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oai:doaj.org-article:027c6235d43c47e7b8c91fcf0e44bef12021-12-02T17:33:04ZHigh precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes10.1038/s41467-018-06758-12041-1723https://doaj.org/article/027c6235d43c47e7b8c91fcf0e44bef12018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06758-1https://doaj.org/toc/2041-1723Nucleosomes compact the genome and regulate access to specific DNA sequences. Here the authors employ single-molecule FRET studies to characterize nucleosome dynamics at different salt concentrations and dissect nucleosome disassembly into elementary steps.Alexander GansenSuren FelekyanRalf KühnemuthKathrin LehmannKatalin TóthClaus A. M. SeidelJörg LangowskiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018) |
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Science Q Alexander Gansen Suren Felekyan Ralf Kühnemuth Kathrin Lehmann Katalin Tóth Claus A. M. Seidel Jörg Langowski High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes |
description |
Nucleosomes compact the genome and regulate access to specific DNA sequences. Here the authors employ single-molecule FRET studies to characterize nucleosome dynamics at different salt concentrations and dissect nucleosome disassembly into elementary steps. |
format |
article |
author |
Alexander Gansen Suren Felekyan Ralf Kühnemuth Kathrin Lehmann Katalin Tóth Claus A. M. Seidel Jörg Langowski |
author_facet |
Alexander Gansen Suren Felekyan Ralf Kühnemuth Kathrin Lehmann Katalin Tóth Claus A. M. Seidel Jörg Langowski |
author_sort |
Alexander Gansen |
title |
High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes |
title_short |
High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes |
title_full |
High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes |
title_fullStr |
High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes |
title_full_unstemmed |
High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes |
title_sort |
high precision fret studies reveal reversible transitions in nucleosomes between microseconds and minutes |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/027c6235d43c47e7b8c91fcf0e44bef1 |
work_keys_str_mv |
AT alexandergansen highprecisionfretstudiesrevealreversibletransitionsinnucleosomesbetweenmicrosecondsandminutes AT surenfelekyan highprecisionfretstudiesrevealreversibletransitionsinnucleosomesbetweenmicrosecondsandminutes AT ralfkuhnemuth highprecisionfretstudiesrevealreversibletransitionsinnucleosomesbetweenmicrosecondsandminutes AT kathrinlehmann highprecisionfretstudiesrevealreversibletransitionsinnucleosomesbetweenmicrosecondsandminutes AT katalintoth highprecisionfretstudiesrevealreversibletransitionsinnucleosomesbetweenmicrosecondsandminutes AT clausamseidel highprecisionfretstudiesrevealreversibletransitionsinnucleosomesbetweenmicrosecondsandminutes AT jorglangowski highprecisionfretstudiesrevealreversibletransitionsinnucleosomesbetweenmicrosecondsandminutes |
_version_ |
1718380040930983936 |