Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

Relatives of patients with amyotrophic lateral sclerosis have an unexpectedly high incidence of schizophrenia. Here, the authors show a genetic link between the two conditions, suggesting shared neurobiological mechanisms.

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Autores principales:	Russell L. McLaughlin, Dick Schijven, Wouter van Rheenen, Kristel R. van Eijk, Margaret O’Brien, René S. Kahn, Roel A. Ophoff, An Goris, Daniel G. Bradley, Ammar Al-Chalabi, Leonard H. van den Berg, Jurjen J. Luykx, Orla Hardiman, Jan H. Veldink, Project MinE GWAS Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/027d962f83034326a2a1dd6510efab44
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spelling	oai:doaj.org-article:027d962f83034326a2a1dd6510efab442021-12-02T15:38:51ZGenetic correlation between amyotrophic lateral sclerosis and schizophrenia10.1038/ncomms147742041-1723https://doaj.org/article/027d962f83034326a2a1dd6510efab442017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14774https://doaj.org/toc/2041-1723Relatives of patients with amyotrophic lateral sclerosis have an unexpectedly high incidence of schizophrenia. Here, the authors show a genetic link between the two conditions, suggesting shared neurobiological mechanisms.Russell L. McLaughlinDick SchijvenWouter van RheenenKristel R. van EijkMargaret O’BrienRené S. KahnRoel A. OphoffAn GorisDaniel G. BradleyAmmar Al-ChalabiLeonard H. van den BergJurjen J. LuykxOrla HardimanJan H. VeldinkProject MinE GWAS ConsortiumSchizophrenia Working Group of the Psychiatric Genomics ConsortiumNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Russell L. McLaughlin Dick Schijven Wouter van Rheenen Kristel R. van Eijk Margaret O’Brien René S. Kahn Roel A. Ophoff An Goris Daniel G. Bradley Ammar Al-Chalabi Leonard H. van den Berg Jurjen J. Luykx Orla Hardiman Jan H. Veldink Project MinE GWAS Consortium Schizophrenia Working Group of the Psychiatric Genomics Consortium Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
description	Relatives of patients with amyotrophic lateral sclerosis have an unexpectedly high incidence of schizophrenia. Here, the authors show a genetic link between the two conditions, suggesting shared neurobiological mechanisms.
format	article
author	Russell L. McLaughlin Dick Schijven Wouter van Rheenen Kristel R. van Eijk Margaret O’Brien René S. Kahn Roel A. Ophoff An Goris Daniel G. Bradley Ammar Al-Chalabi Leonard H. van den Berg Jurjen J. Luykx Orla Hardiman Jan H. Veldink Project MinE GWAS Consortium Schizophrenia Working Group of the Psychiatric Genomics Consortium
author_facet	Russell L. McLaughlin Dick Schijven Wouter van Rheenen Kristel R. van Eijk Margaret O’Brien René S. Kahn Roel A. Ophoff An Goris Daniel G. Bradley Ammar Al-Chalabi Leonard H. van den Berg Jurjen J. Luykx Orla Hardiman Jan H. Veldink Project MinE GWAS Consortium Schizophrenia Working Group of the Psychiatric Genomics Consortium
author_sort	Russell L. McLaughlin
title	Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
title_short	Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
title_full	Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
title_fullStr	Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
title_full_unstemmed	Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
title_sort	genetic correlation between amyotrophic lateral sclerosis and schizophrenia
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/027d962f83034326a2a1dd6510efab44
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Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

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