The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3

The histone variant CENP-A marks active centromeres and replaces H3 at centromeres through a poorly understood mechanism. Here, the authors provide evidence that the chromatin remodeller Ino80 promotes CENP-A chromatin assembly at the centromere in fission yeast.

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Autores principales: Eun Shik Choi, Youngseo Cheon, Keunsoo Kang, Daeyoup Lee
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/02879fff3bb244c6a914ef2df82b912c
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spelling oai:doaj.org-article:02879fff3bb244c6a914ef2df82b912c2021-12-02T14:41:58ZThe Ino80 complex mediates epigenetic centromere propagation via active removal of histone H310.1038/s41467-017-00704-32041-1723https://doaj.org/article/02879fff3bb244c6a914ef2df82b912c2017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00704-3https://doaj.org/toc/2041-1723The histone variant CENP-A marks active centromeres and replaces H3 at centromeres through a poorly understood mechanism. Here, the authors provide evidence that the chromatin remodeller Ino80 promotes CENP-A chromatin assembly at the centromere in fission yeast.Eun Shik ChoiYoungseo CheonKeunsoo KangDaeyoup LeeNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Eun Shik Choi
Youngseo Cheon
Keunsoo Kang
Daeyoup Lee
The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3
description The histone variant CENP-A marks active centromeres and replaces H3 at centromeres through a poorly understood mechanism. Here, the authors provide evidence that the chromatin remodeller Ino80 promotes CENP-A chromatin assembly at the centromere in fission yeast.
format article
author Eun Shik Choi
Youngseo Cheon
Keunsoo Kang
Daeyoup Lee
author_facet Eun Shik Choi
Youngseo Cheon
Keunsoo Kang
Daeyoup Lee
author_sort Eun Shik Choi
title The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3
title_short The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3
title_full The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3
title_fullStr The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3
title_full_unstemmed The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3
title_sort ino80 complex mediates epigenetic centromere propagation via active removal of histone h3
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/02879fff3bb244c6a914ef2df82b912c
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