INFLUENCE OF LOCAL RONKOLEIKIN TREATMENT UPON CLINICAL COURSE OF PURULENT WOUNDS AND FUNCTIONAL ACTIVITY OF WOUND PHAGOCYTES IN PATIENTS WITH ODONTOGENIC PHLEGMONAE

Abstract. The aim of the work was to evaluate clinical features of purulent wounds trend and functional activity of local wound phagocytes in the patients with odontogenic phlegmones in the course of local treatment with Ronkoleukin. A randomized clinical study was performed which included sixty-fiv...

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Autores principales:	I. I. Dolgushin, L. S. Latyushina
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	phagocytes phlegmones ronkoleukin Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/028cadb89cd249b7b3c46143a3c2ff5e
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spelling	oai:doaj.org-article:028cadb89cd249b7b3c46143a3c2ff5e2021-11-18T08:03:41ZINFLUENCE OF LOCAL RONKOLEIKIN TREATMENT UPON CLINICAL COURSE OF PURULENT WOUNDS AND FUNCTIONAL ACTIVITY OF WOUND PHAGOCYTES IN PATIENTS WITH ODONTOGENIC PHLEGMONAE1563-06252313-741X10.15789/1563-0625-2009-1-95-100https://doaj.org/article/028cadb89cd249b7b3c46143a3c2ff5e2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/514https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. The aim of the work was to evaluate clinical features of purulent wounds trend and functional activity of local wound phagocytes in the patients with odontogenic phlegmones in the course of local treatment with Ronkoleukin. A randomized clinical study was performed which included sixty-five patients with odontogenic phlegmones. Their age ranged from 18 to 74 years old. The group was divided in two parts, i.e., patients of a comparison group (n = 33) receiving a conventional combined drug therapy, and the persons from study group (n = 32) who were subject to local immunotherapy with Ronkoleukin, applied along with conventional therapy. It was established that the local therapy with Ronkoleikin exerts distinct positive effects, i.e., increase in wound-located lymphocytes and macrophages, acceleration of phasic dynamics of inflammatory events, augmentation of an lysosomal luminescence index (2.3-fold), enhancement of phagocytosis intensity in wound neutrophiles and macrophages (1.9-2-fold), strengthening the reserve abilities of wound neutrophils (1.3-fold). These effects create favorable conditions for elimination of pathogen and optimal healing of purulent wounds in the patients with odontogenic phlegmones.I. I. DolgushinL. S. LatyushinaSPb RAACIarticlephagocytesphlegmonesronkoleukinImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 11, Iss 1, Pp 95-100 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	phagocytes phlegmones ronkoleukin Immunologic diseases. Allergy RC581-607
spellingShingle	phagocytes phlegmones ronkoleukin Immunologic diseases. Allergy RC581-607 I. I. Dolgushin L. S. Latyushina INFLUENCE OF LOCAL RONKOLEIKIN TREATMENT UPON CLINICAL COURSE OF PURULENT WOUNDS AND FUNCTIONAL ACTIVITY OF WOUND PHAGOCYTES IN PATIENTS WITH ODONTOGENIC PHLEGMONAE
description	Abstract. The aim of the work was to evaluate clinical features of purulent wounds trend and functional activity of local wound phagocytes in the patients with odontogenic phlegmones in the course of local treatment with Ronkoleukin. A randomized clinical study was performed which included sixty-five patients with odontogenic phlegmones. Their age ranged from 18 to 74 years old. The group was divided in two parts, i.e., patients of a comparison group (n = 33) receiving a conventional combined drug therapy, and the persons from study group (n = 32) who were subject to local immunotherapy with Ronkoleukin, applied along with conventional therapy. It was established that the local therapy with Ronkoleikin exerts distinct positive effects, i.e., increase in wound-located lymphocytes and macrophages, acceleration of phasic dynamics of inflammatory events, augmentation of an lysosomal luminescence index (2.3-fold), enhancement of phagocytosis intensity in wound neutrophiles and macrophages (1.9-2-fold), strengthening the reserve abilities of wound neutrophils (1.3-fold). These effects create favorable conditions for elimination of pathogen and optimal healing of purulent wounds in the patients with odontogenic phlegmones.
format	article
author	I. I. Dolgushin L. S. Latyushina
author_facet	I. I. Dolgushin L. S. Latyushina
author_sort	I. I. Dolgushin
title	INFLUENCE OF LOCAL RONKOLEIKIN TREATMENT UPON CLINICAL COURSE OF PURULENT WOUNDS AND FUNCTIONAL ACTIVITY OF WOUND PHAGOCYTES IN PATIENTS WITH ODONTOGENIC PHLEGMONAE
title_short	INFLUENCE OF LOCAL RONKOLEIKIN TREATMENT UPON CLINICAL COURSE OF PURULENT WOUNDS AND FUNCTIONAL ACTIVITY OF WOUND PHAGOCYTES IN PATIENTS WITH ODONTOGENIC PHLEGMONAE
title_full	INFLUENCE OF LOCAL RONKOLEIKIN TREATMENT UPON CLINICAL COURSE OF PURULENT WOUNDS AND FUNCTIONAL ACTIVITY OF WOUND PHAGOCYTES IN PATIENTS WITH ODONTOGENIC PHLEGMONAE
title_fullStr	INFLUENCE OF LOCAL RONKOLEIKIN TREATMENT UPON CLINICAL COURSE OF PURULENT WOUNDS AND FUNCTIONAL ACTIVITY OF WOUND PHAGOCYTES IN PATIENTS WITH ODONTOGENIC PHLEGMONAE
title_full_unstemmed	INFLUENCE OF LOCAL RONKOLEIKIN TREATMENT UPON CLINICAL COURSE OF PURULENT WOUNDS AND FUNCTIONAL ACTIVITY OF WOUND PHAGOCYTES IN PATIENTS WITH ODONTOGENIC PHLEGMONAE
title_sort	influence of local ronkoleikin treatment upon clinical course of purulent wounds and functional activity of wound phagocytes in patients with odontogenic phlegmonae
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/028cadb89cd249b7b3c46143a3c2ff5e
work_keys_str_mv	AT iidolgushin influenceoflocalronkoleikintreatmentuponclinicalcourseofpurulentwoundsandfunctionalactivityofwoundphagocytesinpatientswithodontogenicphlegmonae AT lslatyushina influenceoflocalronkoleikintreatmentuponclinicalcourseofpurulentwoundsandfunctionalactivityofwoundphagocytesinpatientswithodontogenicphlegmonae
_version_	1718422459371225088

INFLUENCE OF LOCAL RONKOLEIKIN TREATMENT UPON CLINICAL COURSE OF PURULENT WOUNDS AND FUNCTIONAL ACTIVITY OF WOUND PHAGOCYTES IN PATIENTS WITH ODONTOGENIC PHLEGMONAE

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