A computational workflow for the expansion of heterologous biosynthetic pathways to natural product derivatives
The top down cheminformatics method is usually used for the reconstitution of heterologous pathway to produce plant natural products. Here, the authors report a bottom up computational workflow for the identification of potential products and the enzymes required to make them in a noscapine pathway...
Guardado en:
Autores principales: | Jasmin Hafner, James Payne, Homa MohammadiPeyhani, Vassily Hatzimanikatis, Christina Smolke |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/028da8f650b347c08f4dc018f0d40cef |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
An Integrated Metabolomic and Genomic Mining Workflow To Uncover the Biosynthetic Potential of Bacteria
por: Maria Maansson, et al.
Publicado: (2016) -
An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters
por: Tingting Hao, et al.
Publicado: (2019) -
Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway
por: Sung Ryeol Park, et al.
Publicado: (2016) -
Characterization and engineering of Streptomyces griseofuscus DSM 40191 as a potential host for heterologous expression of biosynthetic gene clusters
por: Tetiana Gren, et al.
Publicado: (2021) -
Heterologous Expression of the Unusual Terreazepine Biosynthetic Gene Cluster Reveals a Promising Approach for Identifying New Chemical Scaffolds
por: Lindsay K. Caesar, et al.
Publicado: (2020)