EVALUATION OF HEMOGRAM INDICATORS AND CYTOKINE STATUS IN HEALTHY ADOLESCENTS LIVING IN THE INDUSTRIAL CITY OF IRKUTSK REGION

Development of technical progress causes increasing anthropogenic pressure that adversely affect human health. The most important environmental factor is the quality of atmospheric air. Children and adolescents are the most sensitive group to the effects of environmental factors. The aim of the stud...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	L. B. Masnavieva, L. A. Budarina, I. V. Kudaeva
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2013
Materias:	teenagers hemogram cytokines air pollution Science Q
Acceso en línea:	https://doaj.org/article/0295d9c1671d4dc08808768619ef8bf0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0295d9c1671d4dc08808768619ef8bf0
record_format	dspace
spelling	oai:doaj.org-article:0295d9c1671d4dc08808768619ef8bf02021-11-23T06:14:28ZEVALUATION OF HEMOGRAM INDICATORS AND CYTOKINE STATUS IN HEALTHY ADOLESCENTS LIVING IN THE INDUSTRIAL CITY OF IRKUTSK REGION2541-94202587-9596https://doaj.org/article/0295d9c1671d4dc08808768619ef8bf02013-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1574https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Development of technical progress causes increasing anthropogenic pressure that adversely affect human health. The most important environmental factor is the quality of atmospheric air. Children and adolescents are the most sensitive group to the effects of environmental factors. The aim of the study was to examine the performance of hemogram and cytokine status of healthy adolescents living in the industrial cities of Irkutsk region with different levels of technogenic pressure. The healthy adolescents of 14-17 years were examined. Group 1 consisted of teenagers, who are living in the city with high level of air pollution (Angarsk). The control group (group 11) consisted of adolescents from the city with medium level of pollution (Sayansk). Hemogram parameters, the content ofinterleukins-2 and -10, alpha- and gamma-interferon in serum were studied. Statistical processing of the results was performed by nonparametric tests using the software package Statistica 6.0. Differences were considered statistically significant at p < 0,05. An analysis of the performance of hemogram revealed that the number of teenagers from Angarsk stab neutrophils and basophils was significantly lower than in the peer group of Sayansk. The level of hemoglobin and erythrocyte sedimentation rate of teenagers from the group 1 were lower than in the comparison group. Average levels of interleukins-2 and -10 in serum in a group of schoolchildren from Angarsk exceeded those of the surveyed Sayansk. Despite the absence of between-group differences in the content of alpha- and gamma-interferon, the proportion of people with high levels of gamma-interferon in the group 1 was higher and amounted to 36,36 %. 1n this case average group values of all the studied parameters were within the reference levels. 1n general changes were determined for indicators of hemogram and cytokine status in healthy adolescents living in the town with high level of air pollution: specifically higher amount of granulocytic white blood cells and lower levels ofinterleukins-2 and -10. These changes may reflect the response of healthy adolescents to air pollution by chemical pollutants and indicate sensitivity to antigenic exposure and preparednessfor response to it.L. B. MasnavievaL. A. BudarinaI. V. KudaevaScientific Сentre for Family Health and Human Reproduction Problemsarticleteenagershemogramcytokinesair pollutionScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3(1), Pp 96-99 (2013)
institution	DOAJ
collection	DOAJ
language	RU
topic	teenagers hemogram cytokines air pollution Science Q
spellingShingle	teenagers hemogram cytokines air pollution Science Q L. B. Masnavieva L. A. Budarina I. V. Kudaeva EVALUATION OF HEMOGRAM INDICATORS AND CYTOKINE STATUS IN HEALTHY ADOLESCENTS LIVING IN THE INDUSTRIAL CITY OF IRKUTSK REGION
description	Development of technical progress causes increasing anthropogenic pressure that adversely affect human health. The most important environmental factor is the quality of atmospheric air. Children and adolescents are the most sensitive group to the effects of environmental factors. The aim of the study was to examine the performance of hemogram and cytokine status of healthy adolescents living in the industrial cities of Irkutsk region with different levels of technogenic pressure. The healthy adolescents of 14-17 years were examined. Group 1 consisted of teenagers, who are living in the city with high level of air pollution (Angarsk). The control group (group 11) consisted of adolescents from the city with medium level of pollution (Sayansk). Hemogram parameters, the content ofinterleukins-2 and -10, alpha- and gamma-interferon in serum were studied. Statistical processing of the results was performed by nonparametric tests using the software package Statistica 6.0. Differences were considered statistically significant at p < 0,05. An analysis of the performance of hemogram revealed that the number of teenagers from Angarsk stab neutrophils and basophils was significantly lower than in the peer group of Sayansk. The level of hemoglobin and erythrocyte sedimentation rate of teenagers from the group 1 were lower than in the comparison group. Average levels of interleukins-2 and -10 in serum in a group of schoolchildren from Angarsk exceeded those of the surveyed Sayansk. Despite the absence of between-group differences in the content of alpha- and gamma-interferon, the proportion of people with high levels of gamma-interferon in the group 1 was higher and amounted to 36,36 %. 1n this case average group values of all the studied parameters were within the reference levels. 1n general changes were determined for indicators of hemogram and cytokine status in healthy adolescents living in the town with high level of air pollution: specifically higher amount of granulocytic white blood cells and lower levels ofinterleukins-2 and -10. These changes may reflect the response of healthy adolescents to air pollution by chemical pollutants and indicate sensitivity to antigenic exposure and preparednessfor response to it.
format	article
author	L. B. Masnavieva L. A. Budarina I. V. Kudaeva
author_facet	L. B. Masnavieva L. A. Budarina I. V. Kudaeva
author_sort	L. B. Masnavieva
title	EVALUATION OF HEMOGRAM INDICATORS AND CYTOKINE STATUS IN HEALTHY ADOLESCENTS LIVING IN THE INDUSTRIAL CITY OF IRKUTSK REGION
title_short	EVALUATION OF HEMOGRAM INDICATORS AND CYTOKINE STATUS IN HEALTHY ADOLESCENTS LIVING IN THE INDUSTRIAL CITY OF IRKUTSK REGION
title_full	EVALUATION OF HEMOGRAM INDICATORS AND CYTOKINE STATUS IN HEALTHY ADOLESCENTS LIVING IN THE INDUSTRIAL CITY OF IRKUTSK REGION
title_fullStr	EVALUATION OF HEMOGRAM INDICATORS AND CYTOKINE STATUS IN HEALTHY ADOLESCENTS LIVING IN THE INDUSTRIAL CITY OF IRKUTSK REGION
title_full_unstemmed	EVALUATION OF HEMOGRAM INDICATORS AND CYTOKINE STATUS IN HEALTHY ADOLESCENTS LIVING IN THE INDUSTRIAL CITY OF IRKUTSK REGION
title_sort	evaluation of hemogram indicators and cytokine status in healthy adolescents living in the industrial city of irkutsk region
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2013
url	https://doaj.org/article/0295d9c1671d4dc08808768619ef8bf0
work_keys_str_mv	AT lbmasnavieva evaluationofhemogramindicatorsandcytokinestatusinhealthyadolescentslivingintheindustrialcityofirkutskregion AT labudarina evaluationofhemogramindicatorsandcytokinestatusinhealthyadolescentslivingintheindustrialcityofirkutskregion AT ivkudaeva evaluationofhemogramindicatorsandcytokinestatusinhealthyadolescentslivingintheindustrialcityofirkutskregion
_version_	1718417112265916416

EVALUATION OF HEMOGRAM INDICATORS AND CYTOKINE STATUS IN HEALTHY ADOLESCENTS LIVING IN THE INDUSTRIAL CITY OF IRKUTSK REGION

Ejemplares similares