Evaluation of integrin αvβ6 cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis

Evaluation of integrin αvβ6 cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis

Knottin is a cystine knot peptide. Here, the authors develop a knottin-based tracer for positron emission tomography and demonstrate its ability to detect cancer and idiopathic pulmonary fibrosis through selective binding to integrin αvβ6.

Saved in:
Bibliographic Details
Main Authors: Richard H. Kimura, Ling Wang, Bin Shen, Li Huo, Willemieke Tummers, Fabian V. Filipp, Haiwei Henry Guo, Thomas Haywood, Lotfi Abou-Elkacem, Lucia Baratto, Frezghi Habte, Rammohan Devulapally, Timothy H. Witney, Yan Cheng, Suhas Tikole, Subhendu Chakraborti, Jay Nix, Christopher A. Bonagura, Negin Hatami, Joshua J. Mooney, Tushar Desai, Scott Turner, Richard S. Gaster, Andrea Otte, Brendan C. Visser, George A. Poultsides, Jeffrey Norton, Walter Park, Mark Stolowitz, Kenneth Lau, Eric Yang, Arutselvan Natarajan, Ohad Ilovich, Shyam Srinivas, Ananth Srinivasan, Ramasamy Paulmurugan, Juergen Willmann, Frederick T. Chin, Zhen Cheng, Andrei Iagaru, Fang Li, Sanjiv S. Gambhir
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Science
Q
Online Access:https://doaj.org/article/029f63b5dea042f582dd348aecf36a8e
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/029f63b5dea042f582dd348aecf36a8e

Similar Items