Feed-forward alpha particle radiotherapy ablates androgen receptor-addicted prostate cancer

Feed-forward alpha particle radiotherapy ablates androgen receptor-addicted prostate cancer

Radionuclides that emit alpha particles (charged helium nuclei) are currently used clinically to treat cancers including prostate cancer. Here, the authors combine a humanized antibody to an alpha particle emitter, specifically to target a downstream effector of the androgen receptor and create a fe...

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Bibliographic Details
Main Authors: Michael R. McDevitt, Daniel L. J. Thorek, Takeshi Hashimoto, Tatsuo Gondo, Darren R. Veach, Sai Kiran Sharma, Teja Muralidhar Kalidindi, Diane S. Abou, Philip A. Watson, Bradley J. Beattie, Oskar Vilhemsson Timmermand, Sven-Erik Strand, Jason S. Lewis, Peter T. Scardino, Howard I. Scher, Hans Lilja, Steven M. Larson, David Ulmert
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
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Online Access:https://doaj.org/article/02a356c6cc14425c8da1a1e7764743bc
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https://doaj.org/article/02a356c6cc14425c8da1a1e7764743bc

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