Highly efficient generation of GGTA1 biallelic knockout inbred mini-pigs with TALENs.

Highly efficient generation of GGTA1 biallelic knockout inbred mini-pigs with TALENs.

Inbred mini-pigs are ideal organ donors for future human xenotransplantations because of their clear genetic background, high homozygosity, and high inbreeding endurance. In this study, we chose fibroblast cells from a highly inbred pig line called Banna mini-pig inbred line (BMI) as donor nuclei fo...

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Autores principales: Jige Xin, Huaqiang Yang, Nana Fan, Bentian Zhao, Zhen Ouyang, Zhaoming Liu, Yu Zhao, Xiaoping Li, Jun Song, Yi Yang, Qingjian Zou, Quanmei Yan, Yangzhi Zeng, Liangxue Lai
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/02b20fbb396944ca80487ec00c04b5e4
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