Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Peripheral Mononuclear Cells in Patients With Ankylosing Spondylitis

ObjectiveGenetic studies on ankylosing spondylitis (AS) have identified more than 100 pathogenic genes. Building a bridge between these genes and biologically targeted therapies is the current research hotspot.MethodsWe integrated single-cell assaying transposase-accessible chromatin sequencing (scA...

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Bibliographic Details
Main Authors:	Huixuan Xu, Haiyan Yu, Lixiong Liu, Hongwei Wu, Cantong Zhang, Wanxia Cai, Xiaoping Hong, Dongzhou Liu, Donge Tang, Yong Dai
Format:	article
Language:	EN
Published:	Frontiers Media S.A. 2021
Subjects:	ankylosing spondylitis single-cell RNA sequencing single-cell assaying transposase accessible chromatin sequencing NFkB TNF signaling pathway Immunologic diseases. Allergy RC581-607
Online Access:	https://doaj.org/article/02b38754374c4765b29df074b937e432
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Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Peripheral Mononuclear Cells in Patients With Ankylosing Spondylitis

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