Time-Dependent Changes in Hepatic Sphingolipid Accumulation and PI3K/Akt/mTOR Signaling Pathway in a Rat Model of NAFLD

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Time-Dependent Changes in Hepatic Sphingolipid Accumulation and PI3K/Akt/mTOR Signaling Pathway in a Rat Model of NAFLD

Increased lipid bioavailability in a diet favors lipid accumulation, enhancing hepatic lipotoxicity and contributing to insulin resistance (IR) development. The aim of our study was to examine time-dependent alterations in the intrahepatic content of sphingolipids and insulin signaling pathway in ra...

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Autores principales:	Klaudia Sztolsztener, Karolina Konstantynowicz-Nowicka, Ewa Harasim-Symbor, Adrian Chabowski
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	insulin signaling insulin resistance sphingolipid lipid accumulation high-fat diet Biology (General) QH301-705.5 Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/02b4a795e98c41b29d31c6be982f3a36
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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