Petri Net computational modelling of Langerhans cell Interferon Regulatory Factor Network predicts their role in T cell activation

Abstract Langerhans cells (LCs) are able to orchestrate adaptive immune responses in the skin by interpreting the microenvironmental context in which they encounter foreign substances, but the regulatory basis for this has not been established. Utilising systems immunology approaches combining in si...

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Autores principales: Marta E. Polak, Chuin Ying Ung, Joanna Masapust, Tom C. Freeman, Michael R. Ardern-Jones
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/02cd986922db48bba0b3dc4129b8371e
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