miR-15a-3p Protects Against Isoniazid-Induced Liver Injury via Suppressing N-Acetyltransferase 2 Expression
Isoniazid (INH), an effective first-line drug for tuberculosis treatment, has been reported to be associated with hepatotoxicity for decades, but the underlying mechanisms are poorly understood. N-acetyltransferase 2 (NAT2) is a Phase II enzyme that specifically catalyzes the acetylation of INH, and...
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Autores principales: | Xinmei Li, Heng Zhang, Lin Xu, Yuan Jin, Jiao Luo, Chuanhai Li, Kunming Zhao, Yuxin Zheng, Dianke Yu, Yanjie Zhao |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/02d22b49417247feb9466c7a5236654f |
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