microRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury
Maintenance of the function and survival of liver sinusoidal endothelial cells (LSECs) play a crucial role in hepatic ischemia/reperfusion (I/R) injury, a major cause of liver impairment during the surgical treatment. Emerging evidence indicates a critical role of microRNAs in I/R injury. This study...
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De Gruyter
2021
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oai:doaj.org-article:02db13b1282c4d05a2d9fe71d9090e432021-12-05T14:10:41ZmicroRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury2391-541210.1515/biol-2021-0042https://doaj.org/article/02db13b1282c4d05a2d9fe71d9090e432021-04-01T00:00:00Zhttps://doi.org/10.1515/biol-2021-0042https://doaj.org/toc/2391-5412Maintenance of the function and survival of liver sinusoidal endothelial cells (LSECs) play a crucial role in hepatic ischemia/reperfusion (I/R) injury, a major cause of liver impairment during the surgical treatment. Emerging evidence indicates a critical role of microRNAs in I/R injury. This study aims to investigate whether miR-9-5p exerts a protective effect on LSECs.Duan YiMeng YuanyuanGao ZhifengWang XiaoyuZhang HuanDe Gruyterarticlemicrorna-9-5pcxc chemokine receptor-4sinusoidal endothelial cellischemia-reperfusion injuryogd/hg injuryBiology (General)QH301-705.5ENOpen Life Sciences, Vol 16, Iss 1, Pp 375-383 (2021) |
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DOAJ |
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DOAJ |
language |
EN |
topic |
microrna-9-5p cxc chemokine receptor-4 sinusoidal endothelial cell ischemia-reperfusion injury ogd/hg injury Biology (General) QH301-705.5 |
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microrna-9-5p cxc chemokine receptor-4 sinusoidal endothelial cell ischemia-reperfusion injury ogd/hg injury Biology (General) QH301-705.5 Duan Yi Meng Yuanyuan Gao Zhifeng Wang Xiaoyu Zhang Huan microRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury |
description |
Maintenance of the function and survival of liver sinusoidal endothelial cells (LSECs) play a crucial role in hepatic ischemia/reperfusion (I/R) injury, a major cause of liver impairment during the surgical treatment. Emerging evidence indicates a critical role of microRNAs in I/R injury. This study aims to investigate whether miR-9-5p exerts a protective effect on LSECs. |
format |
article |
author |
Duan Yi Meng Yuanyuan Gao Zhifeng Wang Xiaoyu Zhang Huan |
author_facet |
Duan Yi Meng Yuanyuan Gao Zhifeng Wang Xiaoyu Zhang Huan |
author_sort |
Duan Yi |
title |
microRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury |
title_short |
microRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury |
title_full |
microRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury |
title_fullStr |
microRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury |
title_full_unstemmed |
microRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury |
title_sort |
microrna-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury |
publisher |
De Gruyter |
publishDate |
2021 |
url |
https://doaj.org/article/02db13b1282c4d05a2d9fe71d9090e43 |
work_keys_str_mv |
AT duanyi microrna95pprotectsliversinusoidalendothelialcellagainstoxygenglucosedeprivationreperfusioninjury AT mengyuanyuan microrna95pprotectsliversinusoidalendothelialcellagainstoxygenglucosedeprivationreperfusioninjury AT gaozhifeng microrna95pprotectsliversinusoidalendothelialcellagainstoxygenglucosedeprivationreperfusioninjury AT wangxiaoyu microrna95pprotectsliversinusoidalendothelialcellagainstoxygenglucosedeprivationreperfusioninjury AT zhanghuan microrna95pprotectsliversinusoidalendothelialcellagainstoxygenglucosedeprivationreperfusioninjury |
_version_ |
1718371818920738816 |