microRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury

Maintenance of the function and survival of liver sinusoidal endothelial cells (LSECs) play a crucial role in hepatic ischemia/reperfusion (I/R) injury, a major cause of liver impairment during the surgical treatment. Emerging evidence indicates a critical role of microRNAs in I/R injury. This study...

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Autores principales: Duan Yi, Meng Yuanyuan, Gao Zhifeng, Wang Xiaoyu, Zhang Huan
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2021
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Acceso en línea:https://doaj.org/article/02db13b1282c4d05a2d9fe71d9090e43
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spelling oai:doaj.org-article:02db13b1282c4d05a2d9fe71d9090e432021-12-05T14:10:41ZmicroRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury2391-541210.1515/biol-2021-0042https://doaj.org/article/02db13b1282c4d05a2d9fe71d9090e432021-04-01T00:00:00Zhttps://doi.org/10.1515/biol-2021-0042https://doaj.org/toc/2391-5412Maintenance of the function and survival of liver sinusoidal endothelial cells (LSECs) play a crucial role in hepatic ischemia/reperfusion (I/R) injury, a major cause of liver impairment during the surgical treatment. Emerging evidence indicates a critical role of microRNAs in I/R injury. This study aims to investigate whether miR-9-5p exerts a protective effect on LSECs.Duan YiMeng YuanyuanGao ZhifengWang XiaoyuZhang HuanDe Gruyterarticlemicrorna-9-5pcxc chemokine receptor-4sinusoidal endothelial cellischemia-reperfusion injuryogd/hg injuryBiology (General)QH301-705.5ENOpen Life Sciences, Vol 16, Iss 1, Pp 375-383 (2021)
institution DOAJ
collection DOAJ
language EN
topic microrna-9-5p
cxc chemokine receptor-4
sinusoidal endothelial cell
ischemia-reperfusion injury
ogd/hg injury
Biology (General)
QH301-705.5
spellingShingle microrna-9-5p
cxc chemokine receptor-4
sinusoidal endothelial cell
ischemia-reperfusion injury
ogd/hg injury
Biology (General)
QH301-705.5
Duan Yi
Meng Yuanyuan
Gao Zhifeng
Wang Xiaoyu
Zhang Huan
microRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury
description Maintenance of the function and survival of liver sinusoidal endothelial cells (LSECs) play a crucial role in hepatic ischemia/reperfusion (I/R) injury, a major cause of liver impairment during the surgical treatment. Emerging evidence indicates a critical role of microRNAs in I/R injury. This study aims to investigate whether miR-9-5p exerts a protective effect on LSECs.
format article
author Duan Yi
Meng Yuanyuan
Gao Zhifeng
Wang Xiaoyu
Zhang Huan
author_facet Duan Yi
Meng Yuanyuan
Gao Zhifeng
Wang Xiaoyu
Zhang Huan
author_sort Duan Yi
title microRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury
title_short microRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury
title_full microRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury
title_fullStr microRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury
title_full_unstemmed microRNA-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury
title_sort microrna-9-5p protects liver sinusoidal endothelial cell against oxygen glucose deprivation/reperfusion injury
publisher De Gruyter
publishDate 2021
url https://doaj.org/article/02db13b1282c4d05a2d9fe71d9090e43
work_keys_str_mv AT duanyi microrna95pprotectsliversinusoidalendothelialcellagainstoxygenglucosedeprivationreperfusioninjury
AT mengyuanyuan microrna95pprotectsliversinusoidalendothelialcellagainstoxygenglucosedeprivationreperfusioninjury
AT gaozhifeng microrna95pprotectsliversinusoidalendothelialcellagainstoxygenglucosedeprivationreperfusioninjury
AT wangxiaoyu microrna95pprotectsliversinusoidalendothelialcellagainstoxygenglucosedeprivationreperfusioninjury
AT zhanghuan microrna95pprotectsliversinusoidalendothelialcellagainstoxygenglucosedeprivationreperfusioninjury
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