Functional specialization of the small interfering RNA pathway in response to virus infection.

In Drosophila, post-transcriptional gene silencing occurs when exogenous or endogenous double stranded RNA (dsRNA) is processed into small interfering RNAs (siRNAs) by Dicer-2 (Dcr-2) in association with a dsRNA-binding protein (dsRBP) cofactor called Loquacious (Loqs-PD). siRNAs are then loaded ont...

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Bibliographic Details
Main Authors: Joao Trindade Marques, Ji-Ping Wang, Xiaohong Wang, Karla Pollyanna Vieira de Oliveira, Catherine Gao, Eric Roberto Guimaraes Rocha Aguiar, Nadereh Jafari, Richard W Carthew
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
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Online Access:https://doaj.org/article/02dcde7e098749f5a519e21fab07a8d4
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