Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics

Nitric oxide is a volatile free radical second messenger with a large number of biological effects. Here Eroglu et al. develop genetically encoded fluorescent biosensors for nitric oxide and use them to visualise subcellular nitric oxide dynamics in single cells.

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Detalles Bibliográficos
Autores principales: Emrah Eroglu, Benjamin Gottschalk, Suphachai Charoensin, Sandra Blass, Helmut Bischof, Rene Rost, Corina T. Madreiter-Sokolowski, Brigitte Pelzmann, Eva Bernhart, Wolfgang Sattler, Seth Hallström, Tadeusz Malinski, Markus Waldeck-Weiermair, Wolfgang F. Graier, Roland Malli
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/02df81f9cf6b4bff83bc4f0ad4df3c56
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Descripción
Sumario:Nitric oxide is a volatile free radical second messenger with a large number of biological effects. Here Eroglu et al. develop genetically encoded fluorescent biosensors for nitric oxide and use them to visualise subcellular nitric oxide dynamics in single cells.