A Member of the Ferlin Calcium Sensor Family Is Essential for <named-content content-type="genus-species">Toxoplasma gondii</named-content> Rhoptry Secretion

A Member of the Ferlin Calcium Sensor Family Is Essential for <named-content content-type="genus-species">Toxoplasma gondii</named-content> Rhoptry Secretion

ABSTRACT Invasion of host cells by apicomplexan parasites such as Toxoplasma gondii is critical for their infectivity and pathogenesis. In Toxoplasma, secretion of essential egress, motility, and invasion-related proteins from microneme organelles is regulated by oscillations of intracellular Ca2+....

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Autores principales: Bradley I. Coleman, Sudeshna Saha, Seiko Sato, Klemens Engelberg, David J. P. Ferguson, Isabelle Coppens, Melissa B. Lodoen, Marc-Jan Gubbels
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
Toxoplasma gondii
calcium
ferlin
micronemes
protein secretion
rhoptries
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/02ef691e1abc4316a0c22d50ae4b1d0a
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