Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer

Granulomatous/sarcoid-like lesions have been reported in patients treated with immune checkpoint inhibitors (ICIs). Here the authors report the occurrence of “nodal immune flare”, an apparent radiological cancer progression in the nodes characterized by the absence of cancer and the presence of non-...

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Autores principales:	Tina Cascone, Annikka Weissferdt, Myrna C. B. Godoy, William N. William, Cheuk H. Leung, Heather Y. Lin, Sreyashi Basu, Shalini S. Yadav, Apar Pataer, Kyle G. Mitchell, Md Abdul Wadud Khan, Yushu Shi, Cara Haymaker, Luisa M. Solis, Edwin R. Parra, Humam Kadara, Ignacio I. Wistuba, Padmanee Sharma, James P. Allison, Nadim J. Ajami, Jennifer A. Wargo, Robert R. Jenq, Don L. Gibbons, J. Jack Lee, Stephen G. Swisher, Ara A. Vaporciyan, John V. Heymach, Boris Sepesi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/02f55269e7f9462fb8c8389a4b130848
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spelling	oai:doaj.org-article:02f55269e7f9462fb8c8389a4b1308482021-12-02T17:08:39ZNodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer10.1038/s41467-021-25188-02041-1723https://doaj.org/article/02f55269e7f9462fb8c8389a4b1308482021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25188-0https://doaj.org/toc/2041-1723Granulomatous/sarcoid-like lesions have been reported in patients treated with immune checkpoint inhibitors (ICIs). Here the authors report the occurrence of “nodal immune flare”, an apparent radiological cancer progression in the nodes characterized by the absence of cancer and the presence of non-caseating granulomas, in patients with non-small cell lung cancer following neoadjuvant ICI treatment.Tina CasconeAnnikka WeissferdtMyrna C. B. GodoyWilliam N. WilliamCheuk H. LeungHeather Y. LinSreyashi BasuShalini S. YadavApar PataerKyle G. MitchellMd Abdul Wadud KhanYushu ShiCara HaymakerLuisa M. SolisEdwin R. ParraHumam KadaraIgnacio I. WistubaPadmanee SharmaJames P. AllisonNadim J. AjamiJennifer A. WargoRobert R. JenqDon L. GibbonsJ. Jack LeeStephen G. SwisherAra A. VaporciyanJohn V. HeymachBoris SepesiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tina Cascone Annikka Weissferdt Myrna C. B. Godoy William N. William Cheuk H. Leung Heather Y. Lin Sreyashi Basu Shalini S. Yadav Apar Pataer Kyle G. Mitchell Md Abdul Wadud Khan Yushu Shi Cara Haymaker Luisa M. Solis Edwin R. Parra Humam Kadara Ignacio I. Wistuba Padmanee Sharma James P. Allison Nadim J. Ajami Jennifer A. Wargo Robert R. Jenq Don L. Gibbons J. Jack Lee Stephen G. Swisher Ara A. Vaporciyan John V. Heymach Boris Sepesi Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer
description	Granulomatous/sarcoid-like lesions have been reported in patients treated with immune checkpoint inhibitors (ICIs). Here the authors report the occurrence of “nodal immune flare”, an apparent radiological cancer progression in the nodes characterized by the absence of cancer and the presence of non-caseating granulomas, in patients with non-small cell lung cancer following neoadjuvant ICI treatment.
format	article
author	Tina Cascone Annikka Weissferdt Myrna C. B. Godoy William N. William Cheuk H. Leung Heather Y. Lin Sreyashi Basu Shalini S. Yadav Apar Pataer Kyle G. Mitchell Md Abdul Wadud Khan Yushu Shi Cara Haymaker Luisa M. Solis Edwin R. Parra Humam Kadara Ignacio I. Wistuba Padmanee Sharma James P. Allison Nadim J. Ajami Jennifer A. Wargo Robert R. Jenq Don L. Gibbons J. Jack Lee Stephen G. Swisher Ara A. Vaporciyan John V. Heymach Boris Sepesi
author_facet	Tina Cascone Annikka Weissferdt Myrna C. B. Godoy William N. William Cheuk H. Leung Heather Y. Lin Sreyashi Basu Shalini S. Yadav Apar Pataer Kyle G. Mitchell Md Abdul Wadud Khan Yushu Shi Cara Haymaker Luisa M. Solis Edwin R. Parra Humam Kadara Ignacio I. Wistuba Padmanee Sharma James P. Allison Nadim J. Ajami Jennifer A. Wargo Robert R. Jenq Don L. Gibbons J. Jack Lee Stephen G. Swisher Ara A. Vaporciyan John V. Heymach Boris Sepesi
author_sort	Tina Cascone
title	Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer
title_short	Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer
title_full	Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer
title_fullStr	Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer
title_full_unstemmed	Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer
title_sort	nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/02f55269e7f9462fb8c8389a4b130848
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Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer

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