Comparative analisis of the dynamics of glycemia using continuos glucose monitoring during on-pump or off-pump coronary artery bypass grafting

Objective.Using continuous glucose monitoring to determine diagnostic optimisation of metabolic status and perioperative management techniques in coronary heart disease and diabetes mellitus type 2 (DMT2) in order to reduce the risk of perioperative complications.Materials and Methods.We examined 80...

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Autores principales:	Elena Zelikovna Golukhova, Nargiz Magomedgadzhievna Magomedova, Galina Evgen'evna Chebotareva
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2016
Materias:	coronary heart disease type 2 diabetes continuous glucose monitoring cardiopulmonary bypass minimally invasive revascularization Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/02f8b8fbd35641cca8a0b6fb7eb4dffd
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spelling	oai:doaj.org-article:02f8b8fbd35641cca8a0b6fb7eb4dffd2021-11-14T09:00:20ZComparative analisis of the dynamics of glycemia using continuos glucose monitoring during on-pump or off-pump coronary artery bypass grafting2072-03512072-037810.14341/DM7710https://doaj.org/article/02f8b8fbd35641cca8a0b6fb7eb4dffd2016-01-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/7710https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Objective.Using continuous glucose monitoring to determine diagnostic optimisation of metabolic status and perioperative management techniques in coronary heart disease and diabetes mellitus type 2 (DMT2) in order to reduce the risk of perioperative complications.Materials and Methods.We examined 80 patients with ischaemic heart disease, aged 39 to 71 years. Patients were divided into four groups. Separation criteria were the presence of diabetes and the method of myocardial revascularisation. For all patients in the intra- and early postoperative periods the continuous glucose monitoring was performed by CGM System Gold MMT-7102W (Medtronic, USA); also blood glucose level has been controlled by sample testing of venous blood (laboratory glucose oxidase electrochemical method) and capillary blood by portable blood glucose meter (OneTouch Ultra, LifeScan, USA).Results.In our study, average blood glucose levels from the results of measurements with CGMS at different operative stages and in the early postoperative period in four groups of patients were measured. Glucose level monitoring in diabetic patients during coronary revascularisation demonstrated that perioperative hyperglycaemia in patients with coronary artery disease who underwent cardiopulmonary bypass was observed regardless of whether they had metabolic carbohydrate disorders during the preoperative period. The most significant changes in glucose were observed in these patients at the stage of cardiopulmonary bypass, while in patients with T2DM, the glycaemic response to intervention (even with satisfactory preoperative compensation of carbohydrate metabolism) was more intense and less manageable than that in surgical patients without diabetes. When operating on a beating heart, intraoperative hyperglycaemia was observed more frequently in patients with T2DM than in controls at the stage of bypass, but glucose indicators were significantly lower than in groups of patients with T2DM who underwent cardiopulmonary bypass.Conclusion.Given the lack of significant differences between the laboratory glucose rates, data from CGM System Gold and OneTouch Ultra demonstrated that continuous glucose monitoring can reliably assess the presence or absence of metabolic changes in the perioperative period and thus reduce the likelihood of complications.Elena Zelikovna GolukhovaNargiz Magomedgadzhievna MagomedovaGalina Evgen'evna ChebotarevaEndocrinology Research Centrearticlecoronary heart diseasetype 2 diabetescontinuous glucose monitoringcardiopulmonary bypassminimally invasive revascularizationNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 19, Iss 1, Pp 44-52 (2016)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	coronary heart disease type 2 diabetes continuous glucose monitoring cardiopulmonary bypass minimally invasive revascularization Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	coronary heart disease type 2 diabetes continuous glucose monitoring cardiopulmonary bypass minimally invasive revascularization Nutritional diseases. Deficiency diseases RC620-627 Elena Zelikovna Golukhova Nargiz Magomedgadzhievna Magomedova Galina Evgen'evna Chebotareva Comparative analisis of the dynamics of glycemia using continuos glucose monitoring during on-pump or off-pump coronary artery bypass grafting
description	Objective.Using continuous glucose monitoring to determine diagnostic optimisation of metabolic status and perioperative management techniques in coronary heart disease and diabetes mellitus type 2 (DMT2) in order to reduce the risk of perioperative complications.Materials and Methods.We examined 80 patients with ischaemic heart disease, aged 39 to 71 years. Patients were divided into four groups. Separation criteria were the presence of diabetes and the method of myocardial revascularisation. For all patients in the intra- and early postoperative periods the continuous glucose monitoring was performed by CGM System Gold MMT-7102W (Medtronic, USA); also blood glucose level has been controlled by sample testing of venous blood (laboratory glucose oxidase electrochemical method) and capillary blood by portable blood glucose meter (OneTouch Ultra, LifeScan, USA).Results.In our study, average blood glucose levels from the results of measurements with CGMS at different operative stages and in the early postoperative period in four groups of patients were measured. Glucose level monitoring in diabetic patients during coronary revascularisation demonstrated that perioperative hyperglycaemia in patients with coronary artery disease who underwent cardiopulmonary bypass was observed regardless of whether they had metabolic carbohydrate disorders during the preoperative period. The most significant changes in glucose were observed in these patients at the stage of cardiopulmonary bypass, while in patients with T2DM, the glycaemic response to intervention (even with satisfactory preoperative compensation of carbohydrate metabolism) was more intense and less manageable than that in surgical patients without diabetes. When operating on a beating heart, intraoperative hyperglycaemia was observed more frequently in patients with T2DM than in controls at the stage of bypass, but glucose indicators were significantly lower than in groups of patients with T2DM who underwent cardiopulmonary bypass.Conclusion.Given the lack of significant differences between the laboratory glucose rates, data from CGM System Gold and OneTouch Ultra demonstrated that continuous glucose monitoring can reliably assess the presence or absence of metabolic changes in the perioperative period and thus reduce the likelihood of complications.
format	article
author	Elena Zelikovna Golukhova Nargiz Magomedgadzhievna Magomedova Galina Evgen'evna Chebotareva
author_facet	Elena Zelikovna Golukhova Nargiz Magomedgadzhievna Magomedova Galina Evgen'evna Chebotareva
author_sort	Elena Zelikovna Golukhova
title	Comparative analisis of the dynamics of glycemia using continuos glucose monitoring during on-pump or off-pump coronary artery bypass grafting
title_short	Comparative analisis of the dynamics of glycemia using continuos glucose monitoring during on-pump or off-pump coronary artery bypass grafting
title_full	Comparative analisis of the dynamics of glycemia using continuos glucose monitoring during on-pump or off-pump coronary artery bypass grafting
title_fullStr	Comparative analisis of the dynamics of glycemia using continuos glucose monitoring during on-pump or off-pump coronary artery bypass grafting
title_full_unstemmed	Comparative analisis of the dynamics of glycemia using continuos glucose monitoring during on-pump or off-pump coronary artery bypass grafting
title_sort	comparative analisis of the dynamics of glycemia using continuos glucose monitoring during on-pump or off-pump coronary artery bypass grafting
publisher	Endocrinology Research Centre
publishDate	2016
url	https://doaj.org/article/02f8b8fbd35641cca8a0b6fb7eb4dffd
work_keys_str_mv	AT elenazelikovnagolukhova comparativeanalisisofthedynamicsofglycemiausingcontinuosglucosemonitoringduringonpumporoffpumpcoronaryarterybypassgrafting AT nargizmagomedgadzhievnamagomedova comparativeanalisisofthedynamicsofglycemiausingcontinuosglucosemonitoringduringonpumporoffpumpcoronaryarterybypassgrafting AT galinaevgenevnachebotareva comparativeanalisisofthedynamicsofglycemiausingcontinuosglucosemonitoringduringonpumporoffpumpcoronaryarterybypassgrafting
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Comparative analisis of the dynamics of glycemia using continuos glucose monitoring during on-pump or off-pump coronary artery bypass grafting

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