Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin

The extracellular matrix is suggested to play a role in neurogenesis, but it is unclear what role integrin signalling may play in the developing neuroepithelium. Here, in chick, Long et al. show that expression of constitutively active integrin beta-1 enhances neurogenesis via a novel Wnt7 and decor...

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Autores principales:	K. Long, L. Moss, L. Laursen, L. Boulter, C. ffrench-Constant
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0312b409378b441fb277fa061d778e0c
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spelling	oai:doaj.org-article:0312b409378b441fb277fa061d778e0c2021-12-02T17:32:23ZIntegrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin10.1038/ncomms103542041-1723https://doaj.org/article/0312b409378b441fb277fa061d778e0c2016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10354https://doaj.org/toc/2041-1723The extracellular matrix is suggested to play a role in neurogenesis, but it is unclear what role integrin signalling may play in the developing neuroepithelium. Here, in chick, Long et al. show that expression of constitutively active integrin beta-1 enhances neurogenesis via a novel Wnt7 and decorin pathway.K. LongL. MossL. LaursenL. BoulterC. ffrench-ConstantNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q K. Long L. Moss L. Laursen L. Boulter C. ffrench-Constant Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin
description	The extracellular matrix is suggested to play a role in neurogenesis, but it is unclear what role integrin signalling may play in the developing neuroepithelium. Here, in chick, Long et al. show that expression of constitutively active integrin beta-1 enhances neurogenesis via a novel Wnt7 and decorin pathway.
format	article
author	K. Long L. Moss L. Laursen L. Boulter C. ffrench-Constant
author_facet	K. Long L. Moss L. Laursen L. Boulter C. ffrench-Constant
author_sort	K. Long
title	Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin
title_short	Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin
title_full	Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin
title_fullStr	Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin
title_full_unstemmed	Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin
title_sort	integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via wnt7a and decorin
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/0312b409378b441fb277fa061d778e0c
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Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin

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