Dispersion as a waste-clearance mechanism in flow through penetrating perivascular spaces in the brain

Abstract Accumulation of metabolic wastes in the brain is correlated with several neurodegenerative disorders, including Alzheimer’s disease. Waste transport and clearance occur via dispersion, the combined effect of diffusion and advection by flow of fluid. We examine the relative contributions of...

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Bibliographic Details
Main Authors: Daniel E. Troyetsky, Jeffrey Tithof, John H. Thomas, Douglas H. Kelley
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
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Q
Online Access:https://doaj.org/article/0313ce98c27640ceb8a913cd2daae2e4
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