Determinants of vitamin D status in fair-skinned women of childbearing age at northern latitudes.

<h4>Background and objective</h4>Poor vitamin D status during pregnancy has been associated with unfavorable outcomes for mother and child. Thus, adequate vitamin D status in women of childbearing age may be important. The aim of this study is to investigate the determinants of 25-hydrox...

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Autores principales:	Linnea Hedlund, Petra Brembeck, Hanna Olausson
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/03150d03bca94f76816a1dde81dab892
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spelling	oai:doaj.org-article:03150d03bca94f76816a1dde81dab8922021-11-18T07:49:53ZDeterminants of vitamin D status in fair-skinned women of childbearing age at northern latitudes.1932-620310.1371/journal.pone.0060864https://doaj.org/article/03150d03bca94f76816a1dde81dab8922013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23593333/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background and objective</h4>Poor vitamin D status during pregnancy has been associated with unfavorable outcomes for mother and child. Thus, adequate vitamin D status in women of childbearing age may be important. The aim of this study is to investigate the determinants of 25-hydroxyvitamin D (25(OH)D) serum concentrations in women of childbearing age living in Sweden, at latitude 57-58° north.<h4>Method</h4>Eighty four non-pregnant, non-lactating, healthy, fair-skinned women aged between 25-40 years were included. All subjects provided blood samples, four day food records and answered questionnaires about sun exposure and lifestyle. Total serum 25(OH)D was analyzed using Roche Cobas® electrochemoluminiescent immunoassay.<h4>Results</h4>Mean 25(OH)D was 65.8±19.9 nmol/l and 23% of the subjects had concentrations <50 nmol/l. Only 1% had concentrations <25 nmol/l. Determinants of 25(OH)D concentrations were recent sunbed use, recent travel to southern latitude, season, estrogen contraceptive use and use of supplementary vitamin D (R(2) = 0.27).<h4>Conclusion</h4>Every fifth woman had 25(OH)D concentrations <50 nmol/l. About 30% of the variation in vitamin D status was explained by sun exposure, use of vitamin D supplements and use of estrogen contraceptives. Cutaneous vitamin D synthesis seems to be a major contributor to vitamin D status, even at northern latitudes. Thus, recommendations on safe UV-B exposure could be beneficial for vitamin D status.Linnea HedlundPetra BrembeckHanna OlaussonPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 4, p e60864 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Linnea Hedlund Petra Brembeck Hanna Olausson Determinants of vitamin D status in fair-skinned women of childbearing age at northern latitudes.
description	<h4>Background and objective</h4>Poor vitamin D status during pregnancy has been associated with unfavorable outcomes for mother and child. Thus, adequate vitamin D status in women of childbearing age may be important. The aim of this study is to investigate the determinants of 25-hydroxyvitamin D (25(OH)D) serum concentrations in women of childbearing age living in Sweden, at latitude 57-58° north.<h4>Method</h4>Eighty four non-pregnant, non-lactating, healthy, fair-skinned women aged between 25-40 years were included. All subjects provided blood samples, four day food records and answered questionnaires about sun exposure and lifestyle. Total serum 25(OH)D was analyzed using Roche Cobas® electrochemoluminiescent immunoassay.<h4>Results</h4>Mean 25(OH)D was 65.8±19.9 nmol/l and 23% of the subjects had concentrations <50 nmol/l. Only 1% had concentrations <25 nmol/l. Determinants of 25(OH)D concentrations were recent sunbed use, recent travel to southern latitude, season, estrogen contraceptive use and use of supplementary vitamin D (R(2) = 0.27).<h4>Conclusion</h4>Every fifth woman had 25(OH)D concentrations <50 nmol/l. About 30% of the variation in vitamin D status was explained by sun exposure, use of vitamin D supplements and use of estrogen contraceptives. Cutaneous vitamin D synthesis seems to be a major contributor to vitamin D status, even at northern latitudes. Thus, recommendations on safe UV-B exposure could be beneficial for vitamin D status.
format	article
author	Linnea Hedlund Petra Brembeck Hanna Olausson
author_facet	Linnea Hedlund Petra Brembeck Hanna Olausson
author_sort	Linnea Hedlund
title	Determinants of vitamin D status in fair-skinned women of childbearing age at northern latitudes.
title_short	Determinants of vitamin D status in fair-skinned women of childbearing age at northern latitudes.
title_full	Determinants of vitamin D status in fair-skinned women of childbearing age at northern latitudes.
title_fullStr	Determinants of vitamin D status in fair-skinned women of childbearing age at northern latitudes.
title_full_unstemmed	Determinants of vitamin D status in fair-skinned women of childbearing age at northern latitudes.
title_sort	determinants of vitamin d status in fair-skinned women of childbearing age at northern latitudes.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/03150d03bca94f76816a1dde81dab892
work_keys_str_mv	AT linneahedlund determinantsofvitamindstatusinfairskinnedwomenofchildbearingageatnorthernlatitudes AT petrabrembeck determinantsofvitamindstatusinfairskinnedwomenofchildbearingageatnorthernlatitudes AT hannaolausson determinantsofvitamindstatusinfairskinnedwomenofchildbearingageatnorthernlatitudes
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Determinants of vitamin D status in fair-skinned women of childbearing age at northern latitudes.

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