An optimized knight traversal technique to detect multiple faults and Module Sequence Graph based reconfiguration of microfluidic biochip

Abstract Conventional biomedical analysers are replaced by digital microfluidic biochips and they are adequate to integrate different biomedical functions, essential for diverse bioassay operations. From the last decade, microfluidic biochips are getting plenty of acceptances in the field of miscell...

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Autores principales:	Basudev Saha, Mukta Majumder
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	Computer engineering. Computer hardware TK7885-7895 Electronic computers. Computer science QA75.5-76.95
Acceso en línea:	https://doaj.org/article/03205e423b12488998420d3f981d3459
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spelling	oai:doaj.org-article:03205e423b12488998420d3f981d34592021-11-17T13:28:44ZAn optimized knight traversal technique to detect multiple faults and Module Sequence Graph based reconfiguration of microfluidic biochip1751-861X1751-860110.1049/cdt2.12004https://doaj.org/article/03205e423b12488998420d3f981d34592021-01-01T00:00:00Zhttps://doi.org/10.1049/cdt2.12004https://doaj.org/toc/1751-8601https://doaj.org/toc/1751-861XAbstract Conventional biomedical analysers are replaced by digital microfluidic biochips and they are adequate to integrate different biomedical functions, essential for diverse bioassay operations. From the last decade, microfluidic biochips are getting plenty of acceptances in the field of miscellaneous healthcare sectors like DNA analysis, drug discovery and clinical diagnosis. These devices are also bearing a vital role in the area of safety critical applications such as food safety testing, air quality monitoring etc. As these devices are used in safety critical applications, clinical diagnosis and real‐time biomolecular assay operations, these must have properties like precision, reliability and robustness. To accept it for discriminating purposes, the microfluidic device must endorse its preciseness and strength by following sublime testing strategy. Here, an optimized droplet traversal technique is proposed to investigate the multiple defective electrodes of a digital microfluidic biochip by embedding boundary cum row traversal and KNIGHT traversal procedure (based on the famous Knight Tour Problem). The proposed approach also enumerates the traversal time for a fault‐free biochip. In addition to identifying the faulty electrodes, a Module Sequencing Graph based reconfiguration technique is proposed here to reinstate the device for normal bioassay operation.Basudev SahaMukta MajumderWileyarticleComputer engineering. Computer hardwareTK7885-7895Electronic computers. Computer scienceQA75.5-76.95ENIET Computers & Digital Techniques, Vol 15, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Computer engineering. Computer hardware TK7885-7895 Electronic computers. Computer science QA75.5-76.95
spellingShingle	Computer engineering. Computer hardware TK7885-7895 Electronic computers. Computer science QA75.5-76.95 Basudev Saha Mukta Majumder An optimized knight traversal technique to detect multiple faults and Module Sequence Graph based reconfiguration of microfluidic biochip
description	Abstract Conventional biomedical analysers are replaced by digital microfluidic biochips and they are adequate to integrate different biomedical functions, essential for diverse bioassay operations. From the last decade, microfluidic biochips are getting plenty of acceptances in the field of miscellaneous healthcare sectors like DNA analysis, drug discovery and clinical diagnosis. These devices are also bearing a vital role in the area of safety critical applications such as food safety testing, air quality monitoring etc. As these devices are used in safety critical applications, clinical diagnosis and real‐time biomolecular assay operations, these must have properties like precision, reliability and robustness. To accept it for discriminating purposes, the microfluidic device must endorse its preciseness and strength by following sublime testing strategy. Here, an optimized droplet traversal technique is proposed to investigate the multiple defective electrodes of a digital microfluidic biochip by embedding boundary cum row traversal and KNIGHT traversal procedure (based on the famous Knight Tour Problem). The proposed approach also enumerates the traversal time for a fault‐free biochip. In addition to identifying the faulty electrodes, a Module Sequencing Graph based reconfiguration technique is proposed here to reinstate the device for normal bioassay operation.
format	article
author	Basudev Saha Mukta Majumder
author_facet	Basudev Saha Mukta Majumder
author_sort	Basudev Saha
title	An optimized knight traversal technique to detect multiple faults and Module Sequence Graph based reconfiguration of microfluidic biochip
title_short	An optimized knight traversal technique to detect multiple faults and Module Sequence Graph based reconfiguration of microfluidic biochip
title_full	An optimized knight traversal technique to detect multiple faults and Module Sequence Graph based reconfiguration of microfluidic biochip
title_fullStr	An optimized knight traversal technique to detect multiple faults and Module Sequence Graph based reconfiguration of microfluidic biochip
title_full_unstemmed	An optimized knight traversal technique to detect multiple faults and Module Sequence Graph based reconfiguration of microfluidic biochip
title_sort	optimized knight traversal technique to detect multiple faults and module sequence graph based reconfiguration of microfluidic biochip
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/03205e423b12488998420d3f981d3459
work_keys_str_mv	AT basudevsaha anoptimizedknighttraversaltechniquetodetectmultiplefaultsandmodulesequencegraphbasedreconfigurationofmicrofluidicbiochip AT muktamajumder anoptimizedknighttraversaltechniquetodetectmultiplefaultsandmodulesequencegraphbasedreconfigurationofmicrofluidicbiochip AT basudevsaha optimizedknighttraversaltechniquetodetectmultiplefaultsandmodulesequencegraphbasedreconfigurationofmicrofluidicbiochip AT muktamajumder optimizedknighttraversaltechniquetodetectmultiplefaultsandmodulesequencegraphbasedreconfigurationofmicrofluidicbiochip
_version_	1718425524935589888

An optimized knight traversal technique to detect multiple faults and Module Sequence Graph based reconfiguration of microfluidic biochip

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