Bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy

Photoconvertible proteins occupy two color channels thereby limiting multicolour localisation microscopy applications. Here the authors present UnaG, a new green-to-dark photoswitching fluorescent protein for super-resolution imaging, whose activation is based on a noncovalent binding with bilirubin...

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Autores principales:	Jiwoong Kwon, Jong-Seok Park, Minsu Kang, Soobin Choi, Jumi Park, Gyeong Tae Kim, Changwook Lee, Sangwon Cha, Hyun-Woo Rhee, Sang-Hee Shim
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0321226231404acaae779b9ffd021c0d
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spelling	oai:doaj.org-article:0321226231404acaae779b9ffd021c0d2021-12-02T14:41:14ZBright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy10.1038/s41467-019-14067-42041-1723https://doaj.org/article/0321226231404acaae779b9ffd021c0d2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14067-4https://doaj.org/toc/2041-1723Photoconvertible proteins occupy two color channels thereby limiting multicolour localisation microscopy applications. Here the authors present UnaG, a new green-to-dark photoswitching fluorescent protein for super-resolution imaging, whose activation is based on a noncovalent binding with bilirubin.Jiwoong KwonJong-Seok ParkMinsu KangSoobin ChoiJumi ParkGyeong Tae KimChangwook LeeSangwon ChaHyun-Woo RheeSang-Hee ShimNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jiwoong Kwon Jong-Seok Park Minsu Kang Soobin Choi Jumi Park Gyeong Tae Kim Changwook Lee Sangwon Cha Hyun-Woo Rhee Sang-Hee Shim Bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy
description	Photoconvertible proteins occupy two color channels thereby limiting multicolour localisation microscopy applications. Here the authors present UnaG, a new green-to-dark photoswitching fluorescent protein for super-resolution imaging, whose activation is based on a noncovalent binding with bilirubin.
format	article
author	Jiwoong Kwon Jong-Seok Park Minsu Kang Soobin Choi Jumi Park Gyeong Tae Kim Changwook Lee Sangwon Cha Hyun-Woo Rhee Sang-Hee Shim
author_facet	Jiwoong Kwon Jong-Seok Park Minsu Kang Soobin Choi Jumi Park Gyeong Tae Kim Changwook Lee Sangwon Cha Hyun-Woo Rhee Sang-Hee Shim
author_sort	Jiwoong Kwon
title	Bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy
title_short	Bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy
title_full	Bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy
title_fullStr	Bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy
title_full_unstemmed	Bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy
title_sort	bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0321226231404acaae779b9ffd021c0d
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Bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy

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