Structure of the TFIIIC subcomplex τA provides insights into RNA polymerase III pre-initiation complex formation

Transcription factor TFIIIC plays roles in Pol III transcription and in chromatin organization. CryoEM structure of the yeast TFIIIC subcomplex τA, a negative stain reconstruction of τA bound to the TFIIIB subunits Brf1 and TBP and accompanying biochemistry suggest how τA achieves positioning of TFI...

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Autores principales:	Matthias K. Vorländer, Anna Jungblut, Kai Karius, Florence Baudin, Helga Grötsch, Jan Kosinski, Christoph W. Müller
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0338fb67478441cfbefda6b1f35f56f9
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spelling	oai:doaj.org-article:0338fb67478441cfbefda6b1f35f56f92021-12-02T17:18:12ZStructure of the TFIIIC subcomplex τA provides insights into RNA polymerase III pre-initiation complex formation10.1038/s41467-020-18707-y2041-1723https://doaj.org/article/0338fb67478441cfbefda6b1f35f56f92020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18707-yhttps://doaj.org/toc/2041-1723Transcription factor TFIIIC plays roles in Pol III transcription and in chromatin organization. CryoEM structure of the yeast TFIIIC subcomplex τA, a negative stain reconstruction of τA bound to the TFIIIB subunits Brf1 and TBP and accompanying biochemistry suggest how τA achieves positioning of TFIIIB upstream of the TSS and remodeling of the TFIIIC complex during assembly of TFIIIB.Matthias K. VorländerAnna JungblutKai KariusFlorence BaudinHelga GrötschJan KosinskiChristoph W. MüllerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Matthias K. Vorländer Anna Jungblut Kai Karius Florence Baudin Helga Grötsch Jan Kosinski Christoph W. Müller Structure of the TFIIIC subcomplex τA provides insights into RNA polymerase III pre-initiation complex formation
description	Transcription factor TFIIIC plays roles in Pol III transcription and in chromatin organization. CryoEM structure of the yeast TFIIIC subcomplex τA, a negative stain reconstruction of τA bound to the TFIIIB subunits Brf1 and TBP and accompanying biochemistry suggest how τA achieves positioning of TFIIIB upstream of the TSS and remodeling of the TFIIIC complex during assembly of TFIIIB.
format	article
author	Matthias K. Vorländer Anna Jungblut Kai Karius Florence Baudin Helga Grötsch Jan Kosinski Christoph W. Müller
author_facet	Matthias K. Vorländer Anna Jungblut Kai Karius Florence Baudin Helga Grötsch Jan Kosinski Christoph W. Müller
author_sort	Matthias K. Vorländer
title	Structure of the TFIIIC subcomplex τA provides insights into RNA polymerase III pre-initiation complex formation
title_short	Structure of the TFIIIC subcomplex τA provides insights into RNA polymerase III pre-initiation complex formation
title_full	Structure of the TFIIIC subcomplex τA provides insights into RNA polymerase III pre-initiation complex formation
title_fullStr	Structure of the TFIIIC subcomplex τA provides insights into RNA polymerase III pre-initiation complex formation
title_full_unstemmed	Structure of the TFIIIC subcomplex τA provides insights into RNA polymerase III pre-initiation complex formation
title_sort	structure of the tfiiic subcomplex τa provides insights into rna polymerase iii pre-initiation complex formation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0338fb67478441cfbefda6b1f35f56f9
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Structure of the TFIIIC subcomplex τA provides insights into RNA polymerase III pre-initiation complex formation

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