mSphere of Influence: Uncovering New Ways To Control Multidrug Resistance by Dissecting Essential Cell Processes

ABSTRACT Ana L. Flores-Mireles works in the fields of microbial pathogenesis and development of new therapeutics. In this mSphere of Influence article, she reflects on how the papers “Bacterial cell wall biogenesis is mediated by SEDS and PBP polymerase families functioning semi-autonomously” by H....

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Autor principal:	Ana L. Flores-Mireles
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2019
Materias:	multidrug resistant pathogens antibiotics CRISPR essential genes cell wall Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/03392e364dfe486ab595e9c227751ba2
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id	oai:doaj.org-article:03392e364dfe486ab595e9c227751ba2
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spelling	oai:doaj.org-article:03392e364dfe486ab595e9c227751ba22021-11-15T15:27:33ZmSphere of Influence: Uncovering New Ways To Control Multidrug Resistance by Dissecting Essential Cell Processes10.1128/mSphere.00648-192379-5042https://doaj.org/article/03392e364dfe486ab595e9c227751ba22019-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSphere.00648-19https://doaj.org/toc/2379-5042ABSTRACT Ana L. Flores-Mireles works in the fields of microbial pathogenesis and development of new therapeutics. In this mSphere of Influence article, she reflects on how the papers “Bacterial cell wall biogenesis is mediated by SEDS and PBP polymerase families functioning semi-autonomously” by H. Cho et al. (Nat Microbiol 1:16172, 2016, https://doi.org/10.1038/nmicrobiol.2016.172) and “A comprehensive, CRISPR-based functional analysis of essential genes in bacteria” by J. M. Peters et al. (Cell 165:1493–1506, 2016, https://doi.org/10.1016/j.cell.2016.05.003) made an impact on her approach to dissecting essential processes to understand microbial pathogenesis in catheter-associated urinary tract infections and generate an effective treatment with reduced likelihood of developing resistance.Ana L. Flores-MirelesAmerican Society for Microbiologyarticlemultidrug resistantpathogensantibioticsCRISPRessential genescell wallMicrobiologyQR1-502ENmSphere, Vol 4, Iss 5 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	multidrug resistant pathogens antibiotics CRISPR essential genes cell wall Microbiology QR1-502
spellingShingle	multidrug resistant pathogens antibiotics CRISPR essential genes cell wall Microbiology QR1-502 Ana L. Flores-Mireles mSphere of Influence: Uncovering New Ways To Control Multidrug Resistance by Dissecting Essential Cell Processes
description	ABSTRACT Ana L. Flores-Mireles works in the fields of microbial pathogenesis and development of new therapeutics. In this mSphere of Influence article, she reflects on how the papers “Bacterial cell wall biogenesis is mediated by SEDS and PBP polymerase families functioning semi-autonomously” by H. Cho et al. (Nat Microbiol 1:16172, 2016, https://doi.org/10.1038/nmicrobiol.2016.172) and “A comprehensive, CRISPR-based functional analysis of essential genes in bacteria” by J. M. Peters et al. (Cell 165:1493–1506, 2016, https://doi.org/10.1016/j.cell.2016.05.003) made an impact on her approach to dissecting essential processes to understand microbial pathogenesis in catheter-associated urinary tract infections and generate an effective treatment with reduced likelihood of developing resistance.
format	article
author	Ana L. Flores-Mireles
author_facet	Ana L. Flores-Mireles
author_sort	Ana L. Flores-Mireles
title	mSphere of Influence: Uncovering New Ways To Control Multidrug Resistance by Dissecting Essential Cell Processes
title_short	mSphere of Influence: Uncovering New Ways To Control Multidrug Resistance by Dissecting Essential Cell Processes
title_full	mSphere of Influence: Uncovering New Ways To Control Multidrug Resistance by Dissecting Essential Cell Processes
title_fullStr	mSphere of Influence: Uncovering New Ways To Control Multidrug Resistance by Dissecting Essential Cell Processes
title_full_unstemmed	mSphere of Influence: Uncovering New Ways To Control Multidrug Resistance by Dissecting Essential Cell Processes
title_sort	msphere of influence: uncovering new ways to control multidrug resistance by dissecting essential cell processes
publisher	American Society for Microbiology
publishDate	2019
url	https://doaj.org/article/03392e364dfe486ab595e9c227751ba2
work_keys_str_mv	AT analfloresmireles msphereofinfluenceuncoveringnewwaystocontrolmultidrugresistancebydissectingessentialcellprocesses
_version_	1718427927515758592

mSphere of Influence: Uncovering New Ways To Control Multidrug Resistance by Dissecting Essential Cell Processes

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