Symptom- and Prevention-Based Testing of COVID-19 in Nursing Home Residents: A Retrospective Cohort Study

Nursing homes (NH) residents with COVID-19 can either be tested because of presence of core symptoms (S-based) or because of transmission prevention (TP-based). The investigated study sample included all NH residents who underwent SARS-CoV-2 RT-PCR testing between March 16, 2020 and May 31, 2020 ( n...

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Autores principales:	Kelly C. Paap, Anouk M. van Loon, Sarian M. van Rijs, Esther Helmich, Bianca M. Buurman, Martin Smalbrugge, Cees M. P. M. Hertogh
Formato:	article
Lenguaje:	EN
Publicado:	SAGE Publishing 2021
Materias:	Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/033ae2ea9cb448638961e30da6d5ee91
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spelling	oai:doaj.org-article:033ae2ea9cb448638961e30da6d5ee912021-11-11T22:33:33ZSymptom- and Prevention-Based Testing of COVID-19 in Nursing Home Residents: A Retrospective Cohort Study2333-721410.1177/23337214211055338https://doaj.org/article/033ae2ea9cb448638961e30da6d5ee912021-10-01T00:00:00Zhttps://doi.org/10.1177/23337214211055338https://doaj.org/toc/2333-7214Nursing homes (NH) residents with COVID-19 can either be tested because of presence of core symptoms (S-based) or because of transmission prevention (TP-based). The investigated study sample included all NH residents who underwent SARS-CoV-2 RT-PCR testing between March 16, 2020 and May 31, 2020 ( n = 380). Clinical symptoms, temperature, and oxygen saturation were extracted from medical records, 7 days before to 14 days after testing. COVID-19 was confirmed in 81 (21%) residents; 36 (44%) S-based and 45 (56%) TP-based: 45. Cycle threshold (CT) values did not differ between the groups. In the 7 days prior to the test falling (32%), somnolence (25%) and fatigue (21%) occurred in both groups. Two days before the test, we observed a stronger decrease in oxygen saturation and an increase in temperature for the S-based group compared to the T-based group that remained up to 10 days after testing. Residents within the S-based group were 2.5 times more likely to increased mortality within 30 days than residents in the TP-based group (HR, 2.56; 95% 1.3–5.2). Although, 73% of the T-based group did eventually develop core symptoms. Thus, attention to falling and daily measures of temperature and oxygen saturation can contribute to earlier detection.Kelly C. PaapAnouk M. van LoonSarian M. van RijsEsther HelmichBianca M. BuurmanMartin SmalbruggeCees M. P. M. HertoghSAGE PublishingarticleGeriatricsRC952-954.6ENGerontology and Geriatric Medicine, Vol 7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Geriatrics RC952-954.6
spellingShingle	Geriatrics RC952-954.6 Kelly C. Paap Anouk M. van Loon Sarian M. van Rijs Esther Helmich Bianca M. Buurman Martin Smalbrugge Cees M. P. M. Hertogh Symptom- and Prevention-Based Testing of COVID-19 in Nursing Home Residents: A Retrospective Cohort Study
description	Nursing homes (NH) residents with COVID-19 can either be tested because of presence of core symptoms (S-based) or because of transmission prevention (TP-based). The investigated study sample included all NH residents who underwent SARS-CoV-2 RT-PCR testing between March 16, 2020 and May 31, 2020 ( n = 380). Clinical symptoms, temperature, and oxygen saturation were extracted from medical records, 7 days before to 14 days after testing. COVID-19 was confirmed in 81 (21%) residents; 36 (44%) S-based and 45 (56%) TP-based: 45. Cycle threshold (CT) values did not differ between the groups. In the 7 days prior to the test falling (32%), somnolence (25%) and fatigue (21%) occurred in both groups. Two days before the test, we observed a stronger decrease in oxygen saturation and an increase in temperature for the S-based group compared to the T-based group that remained up to 10 days after testing. Residents within the S-based group were 2.5 times more likely to increased mortality within 30 days than residents in the TP-based group (HR, 2.56; 95% 1.3–5.2). Although, 73% of the T-based group did eventually develop core symptoms. Thus, attention to falling and daily measures of temperature and oxygen saturation can contribute to earlier detection.
format	article
author	Kelly C. Paap Anouk M. van Loon Sarian M. van Rijs Esther Helmich Bianca M. Buurman Martin Smalbrugge Cees M. P. M. Hertogh
author_facet	Kelly C. Paap Anouk M. van Loon Sarian M. van Rijs Esther Helmich Bianca M. Buurman Martin Smalbrugge Cees M. P. M. Hertogh
author_sort	Kelly C. Paap
title	Symptom- and Prevention-Based Testing of COVID-19 in Nursing Home Residents: A Retrospective Cohort Study
title_short	Symptom- and Prevention-Based Testing of COVID-19 in Nursing Home Residents: A Retrospective Cohort Study
title_full	Symptom- and Prevention-Based Testing of COVID-19 in Nursing Home Residents: A Retrospective Cohort Study
title_fullStr	Symptom- and Prevention-Based Testing of COVID-19 in Nursing Home Residents: A Retrospective Cohort Study
title_full_unstemmed	Symptom- and Prevention-Based Testing of COVID-19 in Nursing Home Residents: A Retrospective Cohort Study
title_sort	symptom- and prevention-based testing of covid-19 in nursing home residents: a retrospective cohort study
publisher	SAGE Publishing
publishDate	2021
url	https://doaj.org/article/033ae2ea9cb448638961e30da6d5ee91
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Symptom- and Prevention-Based Testing of COVID-19 in Nursing Home Residents: A Retrospective Cohort Study

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